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J Neuropsychiatry Clin Neurosci 15:450-452, November 2003
© 2003 American Psychiatric Press, Inc.


Clinical and Research Reports

Mesial Temporal Structures and Comorbid Anxiety in Refractory Partial Epilepsy

Parthasarathy Satishchandra, D.M., Ennapadam S. Krishnamoorthy, M.D., Ludger Tebartz van Elst, M.D., Louis Lemieux, Ph.D., Mathias Koepp, Ph.D., Richard J. Brown, Ph.D. and Michael R. Trimble, M.D.

Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; m.trimble{at}ion.ucl.ac.uk (E-mail).

ABSTRACT

We used quantitative magnetic resonance imaging (MRI) to examine the mesial temporal structures in subjects with refractory partial epilepsy and comorbid anxiety and found preservation with a right-sided preponderance. The findings indicate a role for this brain region in the genesis of anxiety.




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