Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via HighWire Citing Articles via Google Scholar Articles by Prueter, C. Articles by Norra, C. Search for Related Content PubMed Citation Articles by Prueter, C. Articles by Norra, C. Mood Disorders (General) Epilepsy

Mood Disorders and Their Treatment in Patients With Epilepsy

Received November 5, 2002; revised February 20, 2003; accepted March 25, 2003. From the Department of Psychiatry and Psychotherapy of the Technical University (RWTH), Neuropsychiatric Research Group, University Hospital Aachen, Germany. Address correspondence to Dr. Prueter, Department of Psychiatry and Psychotherapy, University Hospital, Pauwelsstrasse 30, 52074 Aachen, Germany; cprueter{at}ukaachen.de (E-mail.)

Mood disorders in patients with epilepsy are not frequently diagnosed and not treated. Because of the high prevalence of depression and the resulting high suicide rate, precise diagnosis and effective therapy are very important. Frequently, the clinical pictures of depressive syndromes in epileptics do not correspond with those described in operationalized classification systems such as ICD-10 or DSM-IV. The incidence of depressive disorders in epileptics is estimated in the literature to be 30%–70%. Multifactorial pathogenetic models include the type of seizures, the location of the epileptic focus, and neurotransmitter dysfunctions, as well as hereditary and psychosocial influences, and negative psychotropic effects of antiepileptic drugs. Despite an insufficient number of available controlled studies, based on the current data, treatment with the newer serotonergic antidepressants can be recommended for patients with epilepsy.

This article has been cited by other articles:

				R. S Briellmann, M. J Hopwood, and G. D Jackson Major depression in temporal lobe epilepsy with hippocampal sclerosis: clinical and imaging correlates J. Neurol. Neurosurg. Psychiatry, November 1, 2007; 78(11): 1226 - 1230. [Abstract] [Full Text] [PDF]

				E. M. Jutkiewicz The Antidepressant -like Effects of Delta-Opioid Receptor Agonists Mol. Interv., June 1, 2006; 6(3): 162 - 169. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 2005 American Neuropsychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us