Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via HighWire Citing Articles via Google Scholar Articles by Roth, R. M. Articles by O’Connor, K. Search for Related Content PubMed Citation Articles by Roth, R. M. Articles by O’Connor, K. Neuropsychology Obsessive-Compulsive Disorder

Neuropsychological Functioning in Early- and Late-Onset Obsessive-Compulsive Disorder

Received May 12, 2003; revised March 25, 2004; accepted April 5, 2004. From the Neuropsychology Program, Department of Psychiatry, Dartmouth Medical School, Lebanon, New Hampshire; the Department of Psychology, Concordia University, Montréal, Québec, Canada; and the Laboratory of Human Neuropsychology and Neurophysiology, Department of Psychology, Université Laval, Québec, Canada. Address correspondence to Dr. Roth, Dartmouth Medical School/DHMC, Lebanon, New Hampshire, Robert.M.Roth{at}Dartmouth.edu (E-mail).

Significant relationships have been noted between age of onset and demographics, clinical characteristics, and cerebral metabolic activity in obsessive-compulsive disorder (OCD). The authors investigated whether patients with early (N=21) and late (N=17) onset OCD differ with respect to neuropsychological functioning. Results revealed that the late onset OCD group obtained poorer scores on measures of executive function and auditory attention than the early onset group. Late onset OCD was also associated with poorer visual memory relative to healthy comparison subjects. These findings suggest that early and late onset OCD may be the result of at least partially differing neurobiological mechanisms.

Key Words: OCD • Neuropsychology • Onset

This article has been cited by other articles:

				S. R. Chamberlain, N. A. Fineberg, L. A. Menzies, A. D. Blackwell, E. T. Bullmore, T. W. Robbins, and B. J. Sahakian Impaired Cognitive Flexibility and Motor Inhibition in Unaffected First-Degree Relatives of Patients With Obsessive-Compulsive Disorder Am J Psychiatry, February 1, 2007; 164(2): 335 - 338. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 2005 American Neuropsychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us