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Mood and Behavioral Dysfunction With Opsoclonus-Myoclonus Ataxia

Received July 20, 2004; revised January 9, 2005; accepted January 18, 2005. From the Departments of Psychiatry and Pediatrics, Childrens Hospital, Los Angeles University of Southern California Keck School of Medicine. Address correspondence to Dr. Turkel, Childrens Hospital Los Angeles, 4650 Sunset Blvd., #82, Los Angeles, CA 90027; sbturkel{at}usc.edu (E-mail).

ABSTRACT

Opsoclonus-myoclonus ataxia syndrome is a paraneoplastic syndrome of cerebellar damage associated with neuroblastoma. The authors assessed psychiatric symptoms of opsoclonus-myoclonus ataxia syndrome in 17 children, who were 16 months to 12 years of age. Psychiatric symptoms examined included disruptive behavior, affective dysregulation, irritability, impulsivity, cognitive impairment, and poor attention.

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