The Journal of Neuropsychiatry and Clinical Neurosciences
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J Neuropsychiatry Clin Neurosci 18:402-404, August 2006
doi: 10.1176/appi.neuropsych.18.3.402
© 2006 American Neuropsychiatric Association
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Related Collections
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* Parkinson's Disease

Clinical and Research Reports

Preliminary fMRI Evidence of Visual System Dysfunction in Parkinson's Disease Patients With Visual Hallucinations

Suzanne Holroyd, M.D. and G. Frederick Wooten, M.D.

Received January 13, 2005; accepted June 13, 2005. Drs. Holroyd and Wooten are affiliated with the University of Virginia Health System, Charlottesville, Virginia. Address correspondence to Dr. Holroyd, Dept. of Psychiatric Medicine, University of Virginia Health System, Box 800623, Charlottesville, VA 22908; sh4s{at}virginia.edu (E-mail).

ABSTRACT

Using functional magnetic resonance imaging (fMRI), the authors examined visual cortex function in Parkinson's disease patients who did and did not experience visual hallucinations. Patients with visual hallucinations demonstrated increased activation in the visual association cortex and deficits in the primary visual cortex, suggesting that visual hallucinations are associated with an abnormality of visual-cortex function.







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