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J Neuropsychiatry Clin Neurosci 18:405-408, August 2006
doi: 10.1176/appi.neuropsych.18.3.405
© 2006 American Neuropsychiatric Association
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Clinical and Research Reports

Obsessive-Compulsive Symptoms in Heart Disease Patients With and Without History of Rheumatic Fever

Pedro G. Alvarenga, M.D., Ana G. Hounie, Ph.D., Marcos T. Mercadante, Ph.D., Juliana B. Diniz, M.D., Marcos Salem, M.D., Guilherme Spina, M.D. and Eurípedes C. Miguel, Ph.D.

Received October 24, 2004; revised July 26, 2005; accepted August 23, 2005. Drs. Alvarenga, Hounie, Mercadante, Diniz, Salem, and Miguel are affiliated with the Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil. Dr. Spina is affiliated with the Service of Valvular Heart Disease, Heart Institute of the University of São Paulo Medical School, São Paulo, Brazil. Address correspondence to Dr. Alvarenga, Department of Psychiatry, Rua Dr.Ovídeo Pires de Campos 785, Brasil University of Sao Paulo Medical School, São Paulo, Brazil; pedroalva{at}terra.com.br (E-mail).

ABSTRACT

By comparing 51 heart disease patients with history of rheumatic fever and 46 heart disease patients with no rheumatic fever history, the authors found a higher prevalence of obsessive-compulsive symptoms in rheumatic fever subjects. This suggests that rheumatic fever activity is not a necessary condition for the expression of neuropsychiatric symptoms.




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P. G. de Alvarenga, A. G. Hounie, and E. C. Miguel
The Role of Group A {beta}-Hemolytic Streptococcal Infection in Neuropsychiatric Disorders
Pediatrics, November 1, 2008; 122(5): 1157 - 1157.
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