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Apathy in Dementia: An Examination of the Psychometric Properties of the Apathy Evaluation Scale

Received August 24, 2005; revised January 20, 2006; accepted February 4, 2006. Dr. Clarke is affiliated with the Graduate Department of Public Health Sciences and the Institute for Human Development, Life Course and Aging at the University of Toronto, and Department of Psychiatry, Baycrest Centre for Geriatric Care, Toronto, Canada. Dr. van Reekum is affiliated with the Department of Psychiatry and Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, and the Division of Geriatric Psychiatry, University of Toronto, Canada. Dr. Simard is affiliated with the École de Psychologie, Université Laval, Quebec, and the Centre de Recherche-Université Laval-Robert-Giffard, Quebec, Canada. Dr. Streiner is affiliated with the Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, and the Department of Psychiatry, University of Toronto, Canada. Dr. Freedman is affiliated with the Division of Neurology, Behavioural Neurology Program and Rotman Research Institute, Baycrest Centre for Geriatric Care, and the Division of Neurology, Department of Medicine, University of Toronto. Dr. Conn is affiliated with the Department of Psychiatry, Baycrest Center for Geriatric Care, and the Division of Geriatric Psychiatry, University of Toronto, Canada. Address correspondence to Dr. Clarke, Department of Mental Health, Johns Hopkins School of Public Health, Room 802, 624 North Broadway, Baltimore, MD 21205; diana.clarke{at}utoronto.ca (e-mail).

The psychometric properties of the clinician, informant, and self-rated versions of the Apathy Evaluation Scale (AES-C/I/S) were examined using data on 121 outpatients seen in a behavioral neurology clinic for the assessment of dementia and associated neuropsychiatric disorders. Two factors, apathy and interest, were identified for the AES-C and the AES-I. The AES-S had only an apathy factor. The AES-C was found to have fairly good psychometric properties. However, from a diagnostic point of view, the AES-I provided the greatest sensitivity and the strongest positive and negative predictive values. Generally, the AES-S performed poorly compared with the AES-C and AES-I.

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