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Treatment of Apathy With Methylphenidate

Received January 11, 2006; revised May 10, 2006; accepted June 2, 2006. Dr. Padala is affiliated with the Veterans Affairs Medical Center, and University of Nebraska Medical Center, Omaha, Nebraska. Dr. Burke is affiliated with the University of Nebraska Medical Center, Omaha, Nebraska. Drs. Bhatia and Petty are affiliated with the Veterans Affairs Medical Center and Creighton University, Omaha, Nebraska. Address correspondence to Dr. Padala, 4101 Woolworth Avenue, Omaha, NE 68105; ppadala{at}unmc.edu (e-mail).

ABSTRACT

Apathy is a common condition that transcends psychiatric diagnoses. Its treatment is not well studied. The authors present four cases of apathy treated with a regimen of methylphenidate. Significant improvement in apathy and its sub-domains (motivation, novelty, and persistence) were noted.

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