Left Hippocampal Volume Inversely Correlates With Enhanced Emotional Memory in Healthy Middle-Aged Women

doi:10.1176/appi.neuropsych.19.3.335

J Neuropsychiatry Clin Neurosci 19:335-338, August 2007
doi: 10.1176/appi.neuropsych.19.3.335
© 2007 American Neuropsychiatric Association



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Clinical and Research Reports

Left Hippocampal Volume Inversely Correlates With Enhanced Emotional Memory in Healthy Middle-Aged Women

Yutaka Matsuoka, M.D., Ph.D., Mitsue Nagamine , D.Sc., Etsuro Mori, M.D., Ph.D., Shigeru Imoto, M.D., Ph.D., Yoshiharu Kim, M.D., Ph.D. and Yosuke Uchitomi, M.D., Ph.D.

Received June 13, 2006; revised September 22, 2006; accepted September 26, 2006. Drs. Matsuoka and Nagamine are affiliated with the Division of Adult Mental Health, National Institute of Mental Health, Kodaira, and the Psycho-Oncology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa. Dr. Uchitomi is affiliated with the Psycho-Oncology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa. Dr. Mori is affiliated with Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai. Dr. Imoto is affiliated with Breast Surgery Division, National Cancer Center Hospital East, Kashiwa. Dr. Kim is affiliated with the Division of Adult Mental Health, NIMH, National Center of Neurology and Psychiatry, Kodaira. Address correspondence to Dr. Matsuoka, Division of Adult Mental Health, NIMH, National Center of Neurology and Psychiatry, Ogawahigashi 4-1-1, Kodaira, Tokyo 187-8553, Japan; yutaka{at}ncnp.go.jp (e-mail).

ABSTRACT

The authors investigated the effect of hippocampal volume onenhanced emotional memory in 27 healthy women. Irrespectiveof age, education, intracranial volume, cognitive function,delayed recall, and neuroticism, left hippocampal volume showeda significant negative correlation with enhanced emotional memory.

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