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Electrode Placement and Ictal EEG Indices in Electroconvulsive Therapy

Received September 20, 2006; revised December 29, 2006; accepted February 26, 2007. Drs. Rasmussen and Varghese and Ms.Ryan are affiliated with the Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota. Ms. Stevens is affiliated with the Department of Biostatistics, Mayo Clinic, Rochester, Minnesota. Address correspondence to Dr. Rasmussen, Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905; rasmussen.keith{at}mayo.edu (e-mail).

ABSTRACT

The authors determine whether quantitative electroencephalography (EEG) indices in electroconvulsive therapy (ECT) seizures correlate with stimulus electrode placement. The authors analyzed data from ECT seizures involving three electrode placements on 37 different quantitative EEG measures. Though there were a few statistically significant comparisons, no consistent pattern of differences was discerned among the three electrode placements. Though many different EEG analytical indices are available on modern ECT machines, the clinical or neurophysiologic relevance has yet to be established. These data provide a groundwork for future research on the neurophysiological aspects of ECT.

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