Expression of a neural cell adhesion molecule serum fragment is depressed in autism



	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted



	Email this article to a Colleague
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Add to My Articles & Searches
	Download to citation manager



	Citing Articles via Google Scholar



	Articles by Plioplys, A. V.
	Articles by Regan, C. M.
	Search for Related Content



	PubMed Citation
	Articles by Plioplys, A. V.
	Articles by Regan, C. M.

J Neuropsychiatry Clin Neurosci 1990; 2:413-417
Copyright © 1990 by American Neuropsychiatric Association

REGULAR ARTICLES

Expression of a neural cell adhesion molecule serum fragment is depressed in autism

AV Plioplys, SE Hemmens and CM Regan
Department of Pediatrics, University of Toronto.

The level of a neural cell adhesion molecule (NCAM) serum fragment in autism was determined by using an antiserum prepared with immunoaffinity purified mouse NCAM. Autistic patients (N = 16) had statistically significantly decreased serum NCAM levels compared with age-matched controls (p less than 0.0005). This observation could not be attributed to a medication-induced effect. Depressed serum NCAM levels in autism are distinct from schizophrenia, in which serum NCAM levels are elevated.

Get information about faster international access.