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Clinical Correlates of Schizotypy in Patients With Epilepsy

Received August 3, 2007; revised September 6, 2007; accepted September 11, 2007. The authors are affiliated with the Neuropsychiatry Research Group, Department of Neurology, at Amedeo Avogadro University in Novara, Italy. Address correspondence to Marco Mula, M.D., Ph.D., Department of Neurology, Amedeo Avogadro University, C:so Mazzini 18, Novara 28100, Italy; marco.mula{at}med.unipm.it (e-mail).

Clinical correlates of schizotypy were evaluated in 89 adult consecutive outpatients with epilepsy, using the Beck Depression Inventory, the State and Trait Anxiety Inventory, and the Schizotypal Personality Questionnaire (SPQ). Age at onset of the epilepsy significantly correlated with the constricted affect subscale of the SPQ, while a diagnosis of temporal lobe epilepsy correlated with the total SPQ score, the cognitive-perceptual factor of the SPQ, and the suspiciousness subscale of the SPQ. Schizotypal symptoms correlated with early onset of the seizures and a diagnosis of temporal lobe epilepsy, further confirming an association between psychoses and epilepsy.

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