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Predictors of Depression and Anxiety in Patients with Intracranial Neoplasms

Received September 11, 2007; revised October 17, 2007; accepted October 25, 2007. Dr. Brian Appleby and Dr. Rabins are affiliated with the Division of Geriatric Psychiatry and Neuropsychiatry at Johns Hopkins University School of Medicine in Baltimore, M.D.; Dr. Kristin Appleby is affiliated with the Department of Neurology at Georgetown University Hospital in Washington, D.C.; Address correspondence to Brian S. Appleby, M.D., Meyer 279, The Johns Hopkins Hospital, 600 North Wolfe St., Baltimore, MD 21287; bappleb1{at}jhmi.edu (e-mail).

A retrospective review of patients with intracranial neoplasms was performed to identify characteristics of patients with comorbid depression and/or anxiety. This study suggests that depression and anxiety are common comorbidities and that preexisting psychiatric disorders predispose to their occurrence within the neuro-oncology setting.

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