Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via Google Scholar Articles by Morgan, E. E. Search for Related Content Articles by Morgan, E. E.

HIV-Associated Episodic Memory Impairment: Evidence of a Possible Differential Deficit in Source Memory for Complex Visual Stimuli

Received September 14, 2007; revised January 28 and May 23, 2008; accepted June 3, 2008. Ms. Morgan is affiliated with the Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego; Dr. Woods, Ms. Weber, Mr. Dawson, Dr. Carey, Ms. Moran, and Dr. Grant are affiliated with the Department of Psychiatry at the University of California, San Diego. Address correspondence to Steven Paul Woods, Psy.D., HIV Neurobehavioral Research Center, Department of Psychiatry (0847), University of California, San Diego, 150 West Washington St., 2^nd floor, San Diego, CA 92103; spwoods{at}ucsd.edu (e-mail).

The HIV Neurobehavioral Research Center (HNRC) Group

HIV infection is often associated with frontal systems pathology and related deficits in the strategic encoding and retrieval aspects of episodic memory. However, no prior HIV studies have explicitly examined source memory, which refers to recall of information regarding the context in which a declarative memory was formed. Source memory is heavily reliant on frontal systems and strategic cognitive processes and is singly dissociable from the content of the memory (i.e., item memory), which is more dependent on medial temporal systems and automatic processes. The present study examined item and source memory in 60 individuals with HIV infection and 35 demographically similar seronegative participants. The primary finding of interest was a significant HIV effect on source (but not item) memory for complex visual stimuli. Follow-up correlational analyses showed a significant association between visual source memory errors and impairment on measures of executive functions, working memory, and higher-level list learning encoding strategies. These findings extend the hypothesized profile of strategic encoding and retrieval deficits in HIV to the construct of source memory, which may be differentially affected relative to item memory for complex visual stimuli.

Get information about faster international access.

Privacy Policy

Copyright © 2009 American Neuropsychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us