Visual evoked potentials in dementia: selective delay of flash P2 in probable Alzheimer's disease



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	Articles by Coburn, K. L.
	Articles by Moreno, M. A.

J Neuropsychiatry Clin Neurosci 1991; 3:431-435
Copyright © 1991 by American Neuropsychiatric Association

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Visual evoked potentials in dementia: selective delay of flash P2 in probable Alzheimer's disease

KL Coburn, JW Ashford and MA Moreno
Department of Psychiatry, Southern Illinois University School of Medicine, Springfield.

The flash visual evoked potential P2 component is delayed in etiologically mixed groups of demented patients compared to healthy controls or nondemented patients. This study compared patients meeting both DSM-III-R criteria for dementia and NINCDS-ADRDA criteria for probable Alzheimer's disease (AD) with healthy elderly controls and found the P2 delay in the probable AD group. Additional comparisons found no evidence of a P2 delay in demented unlikely AD patients. These results suggest that earlier findings of a delayed P2 in etiologically mixed demented groups may have been due to inclusion of AD patients.

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