J Neuropsychiatry Clin Neurosci 1992; 4:195-197
Copyright © 1992 by American Neuropsychiatric Association
Anticholinergic delirium caused by topical homatropine ophthalmologic solution: confirmation by anticholinergic radioreceptor assay in two cases
LE Tune, FW Bylsma and DC Hilt
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD.
The authors report two patients with prolonged metabolic delirium
presumably initiated by systemic absorption of homatropine from a topical
ophthalmologic solution. Anticholinergic toxicity was confirmed by
muscarinic radioreceptor assay in both cases and by quantitative EEG in one
case.