J Neuropsychiatry Clin Neurosci 1992; 4:214-219
Copyright © 1992 by American Neuropsychiatric Association
Comparing diagnostic tests using information theory: the INFO-ROC technique
E Somoza and D Mossman
Psychiatry Service, Department of Veterans Affairs Medical Center, Cincinnati, OH 45220.
We continue our examination of diagnostic tests that are used to assign
individuals to one of two mutually exclusive categories, those having or
not having a particular disorder. Our last article showed how the
information yielded by a test depends on the choice of cutoff and on the
patient's pre-test probability of having the disorder. In this article, we
demonstrate a method of optimizing a test's information yield that allows
us to determine which of several tests gives the most information. Our
technique allows us to compare a test's performance with that of a perfect
diagnostic test.