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J Neuropsychiatry Clin Neurosci 1992; 4:386-394
Copyright © 1992 by American Neuropsychiatric Association
Neuropsychological performance in asymptomatic HIV infection
RA Bornstein, HA Nasrallah, MF Para, CC Whitacre, P Rosenberger, RJ Fass and R Rice Jr
Department of Psychiatry, Ohio State University, Columbus.
This study compared 74 human immunodeficiency virus (HIV)-negative and 131
HIV-positive asymptomatic homosexual or bisexual men on an extensive
neuropsychological test battery. HIV-positive subjects' performance was
significantly worse on verbal memory and psychomotor skills. The prevalence
of mild but persistent neurobehavioral impairment in the HIV-positive group
was approximately twice that in HIV-negative patients, consistently across
several criteria for impairment. There was evidence that degree of
neuropsychological impairment was related to patients' perceptions of
dysfunction in daily life. Findings were not related to degree of
depression or to medication effects. These data suggest that approximately
10% to 20% of HIV-positive asymptomatic men suffer mild neuropsychological
impairment that influences their daily lives.
This article has been cited by other articles:
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E. C. Kissel, N. D. Pukay-Martin, and R. A. Bornstein
The Relationship Between Age and Cognitive Function in HIV-Infected Men
J Neuropsychiatry Clin Neurosci,
May 1, 2005;
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180 - 184.
[Abstract]
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S. A. Cristiani, N. D. Pukay-Martin, and R. A. Bornstein
Marijuana Use and Cognitive Function in HIV-Infected People
J Neuropsychiatry Clin Neurosci,
August 1, 2004;
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330 - 335.
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J. E. Green, R. V. Saveanu, and R. A. Bornstein
The Effect of Previous Alcohol Abuse on Cognitive Function in HIV Infection
Am J Psychiatry,
February 1, 2004;
161(2):
249 - 254.
[Abstract]
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N. D. Pukay-Martin, S. A. Cristiani, R. Saveanu, and R. A. Bornstein
The Relationship Between Stressful Life Events and Cognitive Function in HIV-Infected Men
J Neuropsychiatry Clin Neurosci,
November 1, 2003;
15(4):
436 - 441.
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T. D. Marcotte, R. Deutsch, J. A. McCutchan, D. J. Moore, S. Letendre, R. J. Ellis, M. R. Wallace, R. K. Heaton, and I. Grant
Prediction of Incident Neurocognitive Impairment by Plasma HIV RNA and CD4 Levels Early After HIV Seroconversion
Arch Neurol,
October 1, 2003;
60(10):
1406 - 1412.
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C.H. Hinkin, S.A. Castellon, R.S. Durvasula, D.J. Hardy, M.N. Lam, K.I. Mason, D. Thrasher, M.B. Goetz, and M. Stefaniak
Medication adherence among HIV+ adults: Effects of cognitive dysfunction and regimen complexity
Neurology,
December 24, 2002;
59(12):
1944 - 1950.
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K. A. Loveland, J. A. Stehbens, E. M. Mahoney, P. A. Sirois, S. Nichols, J. D. Bordeaux, J. M. Watkins, N. Amodei, S. D. Hill, S. Donfield, et al.
Declining Immune Function in Children and Adolescents With Hemophilia and HIV Infection : Effects on Neuropsychological Performance
J. Pediatr. Psychol.,
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