J Neuropsychiatry Clin Neurosci 1992; 4:449-453
Copyright © 1992 by American Neuropsychiatric Association
Dissociation of neurocognitive deficits in a monozygotic twin pair concordant for schizophrenia
R Condray, SR Steinhauer, DP van Kammen and J Zubin
Department of Veterans Affairs Medical Center, Pittsburgh, PA 15206.
Cognitive impairment varies markedly among schizophrenic individuals,
although the reason for this is unknown. A monozygotic twin pair concordant
for schizophrenia was evaluated using electrophysiological and
neurobehavioral measures. Each twin showed a distinctive pattern of
deficits; furthermore, clinical course and electrophysiological activity
were not consonant with social and neurobehavioral functioning. Results
suggest complex interrelationships between neurocognitive functioning and
clinical presentation in schizophrenia.
