SPECT findings in patients with primary mania



	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted



	Email this article to a Colleague
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Add to My Articles & Searches
	Download to citation manager



	Citing Articles via HighWire
	Citing Articles via Google Scholar



	Articles by Migliorelli, R.
	Articles by Robinson, R. G.
	Search for Related Content



	PubMed Citation
	Articles by Migliorelli, R.
	Articles by Robinson, R. G.

J Neuropsychiatry Clin Neurosci 1993; 5:379-383
Copyright © 1993 by American Neuropsychiatric Association

REGULAR ARTICLES

SPECT findings in patients with primary mania

R Migliorelli, SE Starkstein, A Teson, G de Quiros, S Vazquez, R Leiguarda and RG Robinson
Department of Behavioral Neurology, Raul Carrea Institute of Neurological Research, Buenos Aires, Argentina.

Five patients with a manic episode and 7 age-comparable control subjects were studied with single-photon emission computed tomography and [99mTc]d,l-hexamethylpropyleneamine oxime. Manic patients showed significantly lower blood flow in the basal portion of the right temporal lobe compared with normal control subjects. Moreover, manic patients showed a left-right asymmetry (a significantly lower perfusion in the right versus left temporal basal cortex), as well as a dorsal- ventral asymmetry (a significantly lower perfusion in the right temporal basal versus dorsal cortex). These findings suggest that the right basotemporal cortex may play an important role in the production of primary mania.

This article has been cited by other articles:

H. P. Blumberg, J. Kaufman, A. Martin, R. Whiteman, J. H. Zhang, J. C. Gore, D. S. Charney, J. H. Krystal, and B. S. Peterson
Amygdala and Hippocampal Volumes in Adolescents and Adults With Bipolar Disorder
Arch Gen Psychiatry, December 1, 2003; 60(12): 1201 - 1208.
[Abstract] [Full Text] [PDF]

M. A. Carran, C. G. Kohler, M. J. O'Connor, W. B. Bilker, and M. R. Sperling
Mania following temporal lobectomy
Neurology, September 23, 2003; 61(6): 770 - 774.
[Abstract] [Full Text] [PDF]

L. Clark, S. D. Iversen, and G. M. Goodwin
A Neuropsychological Investigation of Prefrontal Cortex Involvement in Acute Mania
Am J Psychiatry, October 1, 2001; 158(10): 1605 - 1611.
[Abstract] [Full Text] [PDF]

H. P. Blumberg, E. Stern, S. Ricketts, D. Martinez, J. de Asis, T. White, J. Epstein, N. Isenberg, P. A. McBride, I. Kemperman, et al.
Rostral and Orbital Prefrontal Cortex Dysfunction in the Manic State of Bipolar Disorder
Am J Psychiatry, December 1, 1999; 156(12): 1986 - 1988.
[Abstract] [Full Text]

Get information about faster international access.