J Neuropsychiatry Clin Neurosci 1993; 5:409-414
Copyright © 1993 by American Neuropsychiatric Association
EEG power modifications in panic disorder during a temporolimbic activation task: relationships with temporal lobe clinical symptomatology
M Locatelli, L Bellodi, G Perna and S Scarone
Department of Biomedical and Technological Sciences, University of Milan Medical School, Italy.
Computerized EEG activity derived from the temporal lobes was investigated
in normal subjects and panic disorder patients with and without
depersonalization and/or derealization, in a resting condition and during
an odor stimulation task. Panic patients without depersonalization or
derealization showed an increase of fast and a decrease of slow activities
independent of odor stimulation. Panic patients with depersonalization
and/or derealization showed an increase of slow activity and bilateral lack
of responsiveness in the fast alpha frequency band during odor stimulation.
Findings suggest there are different EEG patterns in the temporal regions
of the two different groups of panic patients during rest and activating
conditions.