|
| | |
|
J Neuropsychiatry Clin Neurosci 1995; 7:54-60
Copyright © 1995 by American Neuropsychiatric Association
Positive and negative neuropsychiatric features in Alzheimer's disease
RS Doody, P Massman, R Mahurin and S Law
Baylor College of Medicine, Alzheimer's Disease Research Center, Houston, Texas 77030, USA.
Positive neuropsychiatric features (paranoia, delusions, hallucinations)
and negative features (disinterest/withdrawal, apathy, reduced speech
output, reduced physical activity) occur in Alzheimer's disease (AD),
although most studies have focused on positive features alone. Positive
features may be associated with a more severe and rapidly progressive
subtype of AD. A retrospective analysis of prospectively obtained research
data (101 probable AD patients) revealed that patients with positive
features had been ill longer but were otherwise similar to patients with
negative features. Patients with any neuropsychiatric features had more
rapid progression and more severe cognitive and comprehension deficits than
patients without such features. Neuropsychiatric features in AD likely
reflect variations in mesocortical and mesolimbic degeneration rather than
an etiologic or prognostic subtype.
This article has been cited by other articles:
|
|
|
|
 
V. Rao, J. R. Spiro, D. J. Schretlen, and N. G. Cascella
Apathy Syndrome After Traumatic Brain Injury Compared With Deficits in Schizophrenia
Psychosomatics,
June 1, 2007;
48(3):
217 - 222.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
U. Lueken, U. Seidl, L. Volker, E. Schweiger, A. Kruse, and J. Schroder
Development of a Short Version of the Apathy Evaluation Scale Specifically Adapted for Demented Nursing Home Residents
Am J Geriatr Psychiatry,
May 1, 2007;
15(5):
376 - 385.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. Borroni, M. Grassi, C. Agosti, S. Archetti, C. Costanzi, C. Cornali, C. Caltagirone, L. Caimi, M. Di Luca, and A. Padovani
Cumulative Effect of COMT and 5-HTTLPR Polymorphisms and Their Interaction With Disease Severity and Comorbidities on the Risk of Psychosis in Alzheimer Disease
Am J Geriatr Psychiatry,
April 1, 2006;
14(4):
343 - 351.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. A. Ropacki and D. V. Jeste
Epidemiology of and Risk Factors for Psychosis of Alzheimer's Disease: A Review of 55 Studies Published From 1990 to 2003
Am J Psychiatry,
November 1, 2005;
162(11):
2022 - 2030.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. D. Rankin and R. D. Layne
The Use of Olanzapine in the Treatment of Negative Symptoms in Alzheimer's Disease
J Neuropsychiatry Clin Neurosci,
August 1, 2005;
17(3):
423 - 424.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. van Reekum, D. T. Stuss, and L. Ostrander
Apathy: Why Care?
J Neuropsychiatry Clin Neurosci,
February 1, 2005;
17(1):
7 - 19.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. M. Bassiony and C. G. Lyketsos
Delusions and Hallucinations in Alzheimer's Disease: Review of the Brain Decade
Psychosomatics,
October 1, 2003;
44(5):
388 - 401.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. B. Colling
Passive behaviors in Alzheimer' disease: A descriptive analysis
American Journal of Alzheimer's Disease and Other Dementias,
January 1, 1999;
14(1):
27 - 40.
[Abstract]
[PDF]
|
|
|
|
|
|
|
N. Hirono, E. Mori, M. Yasuda, Y. Ikejiri, T. Imamura, T. Shimomura, M. Ikeda, M. Hashimoto, and H. Yamashita
Factors associated with psychotic symptoms in Alzheimer's disease
J. Neurol. Neurosurg. Psychiatry,
May 1, 1998;
64(5):
648 - 652.
[Abstract]
[Full Text]
[PDF]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 1995
American Neuropsychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
