J Neuropsychiatry Clin Neurosci 1995; 7:61-67
Copyright © 1995 by American Neuropsychiatric Association
Quantified electroencephalographic correlates of neuropsychological deficits in Alzheimer's disease
D Pozzi, M Petracchi, L Sabe, A Golimstock, H Garcia and S Starkstein
Department of Behavioral Neurology, Raul Carrea Institute of Neurological Research, Buenos Aires, Argentina.
The authors examined relationships between quantified EEG (qEEG) variables
and neuropsychological performance in 54 consecutive patients with probable
Alzheimer's disease (AD). Patients were studied with qEEG and a
neuropsychological battery that assessed memory, attention, verbal
functions, set-shifting abilities, and procedural learning. More severe
memory, attention, and verbal deficits were significantly correlated with
lower alpha relative power, and increased theta relative power was
significantly correlated with poor set-shifting abilities. No qEEG
variables were significantly correlated with the procedural learning task.
These correlations between deficits in specific cognitive domains and qEEG
bands suggest that qEEG may have an important role in the investigation of
the cognitive deficits in AD.
