J Neuropsychiatry Clin Neurosci 1996; 8:99-103
Copyright © 1996 by American Neuropsychiatric Association
Recall and recognition memory in obsessive-compulsive disorder
CR Savage, NJ Keuthen, MA Jenike, HD Brown, L Baer, AD Kendrick, EC Miguel, SL Rauch and MS Albert
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129-2060, USA. savage@psych.mgh.harvard.edu
This study examined recall and recognition memory in 20 nonmedicated
patients with obsessive-compulsive disorder (OCD) and 20 matched control
subjects. As hypothesized, OCD subjects showed abnormalities affecting
delayed recall of nonverbal information but showed normal recognition.
These results are interpreted as providing preliminary evidence of a
nonverbal memory retrieval deficit consistent with proposed corticostriatal
system dysfunction in OCD.