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J Neuropsychiatry Clin Neurosci 1997; 9:37-44
Copyright © 1997 by American Neuropsychiatric Association


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Subjective complaints versus actual cognitive deficits in predominantly symptomatic HIV-1 seropositive individuals

LH Moore, WG van Gorp, CH Hinkin, MJ Stern, T Swales and P Satz
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, School of Medicine, USA.

The relationship of self-reported cognitive, motor, and affective complaints to actual neuropsychological functioning was explored in a cohort of predominantly symptomatic HIV-1 seropositive individuals. Ninety-two symptomatic HIV-1 infected subjects were questioned about complaints common in HIV infection and were assessed with a comprehensive neuropsychological test battery. No relationship was found between subjective complaints and cognitive functioning, yet a significant relationship was found between self-reported difficulties and formal measures of affect and mood. Failure to show a relationship between self-reported cognitive status and actual neuropsychological functioning in this cohort suggests that complaints of cognitive decline may be attributable to emotional factors.


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