J Neuropsychiatry Clin Neurosci 1997; 9:277-279
Copyright © 1997 by American Neuropsychiatric Association
AIDS mania
CG Lyketsos, J Schwartz, M Fishman and G Treisman
AIDS Psychiatry Service and Neuropsychiatry and Memory Group, Johns Hopkins University, Baltimore, Maryland 21287, USA.
Twenty patients with HIV infection and mania were grouped according to
whether their first manic episode occurred when CD4 count was < 200
(late onset) or > or = 200 (early onset). The late-onset patients were
less likely to have personal or family histories of mood disorder and more
likely to have dementia or cognitive slowing. They also exhibited a
different manic symptom profile. The different sociodemographic and symptom
profiles associated with early-onset and late-onset mania may reflect
differences in pathophysiology.
