J Neuropsychiatry Clin Neurosci 1997; 9:280-282
Copyright © 1997 by American Neuropsychiatric Association
Frontal cortical atrophy and negative symptoms in patients with chronic alcohol dependence
RB Rosse, RL Riggs, AM Dietrich, BL Schwartz and SI Deutsch
Psychiatry Service, Department of Veterans Affairs Medical Center, Washington, DC 20422, USA.
It has been suggested that frontal lobe pathology is associated with
negative symptoms in patients with chronic alcoholism. In his exploratory
study, the authors examined 19 chronic alcoholic inpatients on an alcohol
treatment unit and found a significant relationship between severity of
frontal atrophy (as measured by CT) and negative symptoms (as measured by
the Scale for the Assessment of Negative Symptoms).
