The Journal of Neuropsychiatry
& Clinical Neurosciences

Official Journal of the American Neuropsychiatric Association Editor: Stuart C. Yudofsky, M.D.
Deputy Editors: David B. Arciniegas, M.D. and Robert E. Hales, M.D., M.B.A.
REGULAR ARTICLES  |  April 1, 2014
Hippocampal and Subcortical Alterations of First-Episode, Medication-NaÏve Major Depressive Disorder With Panic Disorder Patients

The authors conducted a subcortical analysis of first-episode, medication-naÏ ve patients with major depressive disorder comorbid with panic disorder. The patient group had smaller volumes of left hippocampus, thalamus, and putamen. Subcortical and hippocampal volumes in the patient group showed significant negative correlations with symptom severity.

REGULAR ARTICLES  |  April 1, 2014
Functional Magnetic Resonance Imaging Study of Apathy in Alzheimer’s Disease

An fMRI study was launched to understand mechanisms of Alzheimer’s disease (AD) patients with apathy. The authors reviewed seven AD patients with apathy and six AD patients without apathy. Under “sad versus neutral” stimulation, non-apathetic AD patients had increased activity in bilateral amygdala and bilateral fusiform gyrus, whereas apathetic AD patients only had increased activities in bilateral fusiform gyrus. Thus, the amygdala was the possible anatomical structure related to apathy in AD patients.

Special Articles  |  April 1, 2014
Systematic Review of Neuroimaging Correlates of Executive Functioning: Converging Evidence From Different Clinical Populations

Executive functioning (EF) is an important cognitive domain that is negatively affected in a number of neuropsychiatric conditions. The authors found that the frontal, parietal, and cerebellar lobes were most frequently associated with EF when comparing results from different clinical populations; the occipital lobe was not correlated with EF in any group.

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