The Journal of Neuropsychiatry
& Clinical Neurosciences

Official Journal of the American Neuropsychiatric Association Editor: Stuart C. Yudofsky, M.D.
Deputy Editors: David B. Arciniegas, M.D. and Robert E. Hales, M.D., M.B.A.
Special Articles  |  July 1, 2014
Toward an Understanding of Decision Making in Severe Mental Illness

A commonality of patients with major psychiatric disorders is their propensity to make poor decisions, which is intimately related to poor real-life outcomes. The authors reviewed the literature on decision making as applied to severe psychiatric disorders, with particular focus on advances in cognitive neuroscience.

REGULAR ARTICLES  |  July 1, 2014
Association Between Clinical Measures and Florbetapir F18 PET Neuroimaging in Mild or Moderate Alzheimer’s Disease Dementia

The authors conducted a retrospective, cross-sectional analysis comparing baseline neuropsychiatric and other clinical characteristics in 199 expert-diagnosed mild and moderate Alzheimer’s dementia patients participating in industry-sponsored clinical trials of an investigational therapy, where 18% lacked florbetapir positron emission tomography (PET) evidence of Alzheimer’s neuropathology.

REGULAR ARTICLES  |  July 1, 2014
Pallidal Stimulation in Parkinson’s Disease Does Not Induce Apathy

Twenty consecutive parkinsonian patients who underwent bilateral pallidal stimulation were assessed 3 months prior to surgery and at both 3 and 6 months after surgery, using psychiatric, neuropsychological, and motor scales. The main finding was the absence of deterioration in psychiatric and cognitive scores 3 months and 6 months after pallidal stimulation.

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