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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 6, Issue 4

November 1994

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November 1994

The frontal lobes and neuropsychiatric illness

Pages:341–477
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.341

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November 1994

The significance of frontal system disorders for medical practice and health policy

Pages:343–347
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.343

Abstract
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In major chronic diseases, apathy or impaired executive cognitive function (ECF) can reduce the patient's ability to cope with the disease and its treatment and to maintain personal safety, dignity, and goal-directed activity. Psychometric and imaging ...

November 1994

Working memory dysfunction in schizophrenia

Pages:348–357
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.348

Abstract
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Recent advances in anatomical, behavioral, and physiological techniques have produced new information about the nature of prefrontal function, its cellular basis, and its anatomical underpinnings in nonhuman primates. These findings are changing our views ...

November 1994

Frontal-subcortical circuits and neuropsychiatric disorders

Pages:358–370
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.358

Abstract
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Five parallel anatomic circuits link regions of the frontal cortex to the striatum, globus pallidus/substantia nigra, and thalamus. The circuits originate in the supplementary motor area, frontal eye fields, dorsolateral prefrontal region, lateral orbito-...

November 1994

Lateralization of frontal lobe functions and cognitive novelty

Pages:371–378
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.371

Abstract
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The two hemispheres are functionally different in ways not adequately captured by the classic distinction between linguistic and nonlinguistic processes. The right hemisphere is critical for processing novel cognitive situations. The left hemisphere is ...

November 1994

The regional prefrontal syndromes: a theoretical and clinical overview

Pages:379–387
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.379

Abstract
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This article provides a broad theoretical and clinical overview of the three regional prefrontal syndromes. An understanding of the extended neural connectivity of the prefrontal cortex provides the template for describing the three distinct prefrontal ...

November 1994

Diagnosis and treatment of patients with "frontal lobe" syndromes

Pages:388–398
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.388

Abstract
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Nine case descriptions illustrate the three major prefrontal syndromes seen in clinical practice: disorganized type, disinhibited type, and apathetic type. A mixture of symptoms from each subtype is usually seen, but dysfunction in one prefrontal system ...

November 1994

Assessment of frontal lobe functions

Pages:399–410
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.399

Abstract
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The authors describe methods for conducting a thorough assessment of functions subserved by the frontal lobes, employing both bedside and psychometric methods of assessing frontal subsystems. Qualitative or process aspects of frontal behavior observable ...

November 1994

Treatment strategies for patients with dysexecutive syndromes

Pages:411–418
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.411

Abstract
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Patients with prefrontal behavioral syndromes (dysexecutive, disinhibited, and apathetic) present a significant therapeutic challenge that demands the integration of psychopharmacologic, behavioral, and systemic interventions. Unfortunately, the ...

November 1994

The frontal lobes and schizophrenia [published erratum appears in J Neuropsychiatry Clin Neurosci 1995 Winter;7(1):121]

Pages:419–427
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.419

Abstract
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Many patients with schizophrenia show clinical signs of frontal lobe dysfunction, including blunted affect, difficulty with problem solving, and impoverished thinking. The authors present cytoarchitectural, neuropsychological, and functional ...

November 1994

Frontal lobe dysfunction in secondary depression

Pages:428–442
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.428

Abstract
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Depression is common in patients with neurological disease, particularly with diseases involving the basal ganglia. Although the mechanisms of mood disorders in these patients are poorly understood, selective neural pathways affected directly and ...

November 1994

The frontal lobes and traumatic brain injury

Pages:443–454
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.443

Abstract
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The authors review 1) the pathophysiological, neuroimaging, and neurobehavioral evidence for frontal lobe involvement in closed head injury; 2) studies elucidating the cognitive deficits and behavioral disturbance related to frontal lobe lesions ...

November 1994

The frontal lobes and content-specific delusions

Pages:455–466
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.455

Abstract
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Contemporary research has shown that delusions are often the product of identifiable neurologic disease, particularly when the delusions have a specific theme or are confined to one topic--monosymptomatic or content- specific delusions. Although these ...

November 1994

Neurosurgical treatment for refractory obsessive-compulsive disorder: implications for understanding frontal lobe function

Pages:467–477
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.467

Abstract
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A minority of patients with obsessive-compulsive disorder (OCD) have a chronic course and extreme disability, with symptoms refractory to pharmacological and psychological treatment. Considerable uncontrolled evidence suggests such cases may respond to ...

Article

November 1994

Clinical Syndromes in Adult Neuropsychology: The Practitioner's Handbook

Alice Medalia

Page:478
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.478

PDF/EPUB

November 1994

Psychotherapy of the Brain-Injured Patient: Reclaiming the Shattered Self

Irwin W. Pollack

Pages:478-a–479
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.478-a

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November 1994

Page:492
Published Online:1 April 2006

https://doi.org/10.1176/jnp.6.4.492

Abstract
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In Figure 2 of P. Trzepacz et al., "SPECT Scan and Cognitive Findings in Subclinical Hepatic Encephalopathy" (Spring 1994; 6:170-175), the legend is incorrect. The black bars represent data for cirrhosis patients, the white bars data for normal control ...

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