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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 9, Issue 3

August 1997

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Article

August 1997

Introduction to the Neuropsychiatry of Limbic and Subcortical Disorders

Stephen Salloway,
Paul Malloy, and
Jeffrey Cummings

Pages:313–314
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.313

PDF/EPUB

August 1997

The limbic system: an anatomic, phylogenetic, and clinical perspective

Pages:315–330
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.315

Abstract
PDF/EPUB

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The limbic system is the border zone where psychiatry meets neurology. The authors provide a model of limbic function that combines phylogenetic, anatomic, functional, and clinical data to interpret diseases relevant to neuropsychiatry. They provide ...

August 1997

Ventromedial temporal lobe anatomy, with comments on Alzheimer's disease and temporal injury

Pages:331–341
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.331

Abstract
PDF/EPUB

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The ventromedial temporal area has a complicated topography and neuroanatomy that has yielded secrets only grudgingly. The major features of surface topography are reviewed here as well as recent neuroanatomical findings that establish the ventromedial ...

August 1997

The thalamus and neuropsychiatric illness

Pages:342–353
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.342

Abstract
PDF/EPUB

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Although the cerebral cortex is usually thought of as a likely substrate for psychiatric disease, the close relationship of thalamus to cortex, both structurally and functionally, argues for much closer consideration of this structure in both research and ...

August 1997

The accumbens: beyond the core-shell dichotomy

Pages:354–381
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.354

Abstract
PDF/EPUB

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This article highlights recent discoveries related to the accumbens and closely associated structures, with special reference to their importance in neuropsychiatry. The development of "striatal patches" in the accumbens is reviewed in a series of ...

August 1997

Neurobiology of fear responses: the role of the amygdala

Pages:382–402
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.382

Abstract
PDF/EPUB

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Evidence from many different laboratories using a variety of experimental techniques and animal species indicates that the amygdala plays a crucial role in conditioned fear and anxiety, as well as attention. Many amygdaloid projection areas are critically ...

August 1997

Paroxysmal limbic disorders in neuropsychiatry

Pages:403–419
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.403

Abstract
PDF/EPUB

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Patients who experience episodes with a transient disturbance in perception, memory, mood, and level of anxiety are frequently encountered by neurologists, psychiatrists, and psychologists. The possibilities for differential diagnosis of these episodes ...

August 1997

Auras and experiential responses arising in the temporal lobe

Pages:420–428
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.420

Abstract
PDF/EPUB

Preview Abstract

Complex partial seizures and the auras that precede them are often manifestations of localized temporal lobe activity. Auras, unlike complex partial seizures, are reportable, since memory for them is retained. Similar experiences can be elicited by local ...

August 1997

Neuropsychiatric symptoms from the temporolimbic lobes

Pages:429–438
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.429

Abstract
PDF/EPUB

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Neuropsychiatric symptoms are common manifestations of temporolimbic lesions. These neuropsychiatric symptoms result from disturbances of specific temporolimbic networks, including medial limbic circuits, lateral limbic circuits, and the "extended" ...

August 1997

The neurobiology of emotional experience

Pages:439–448
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.439

Abstract
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The author discusses a neurological model of a modular network that mediates emotional experience. According to this theory, emotional experience has three components: valence (positive and negative), arousal, and motor activation (approach, avoid, ...

August 1997

The neurobiology of recovery memory

Pages:449–459
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.449

Abstract
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The so-called recovery memory syndrome--reports by adults of recovered memories of childhood sexual abuse and trauma that were allegedly "repressed" for many years--has become an important issue in the field of mental health. In particular, there is ...

August 1997

The medial temporal lobe in schizophrenia

Pages:460–470
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.460

Abstract
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Evidence from diverse avenues of research has highlighted abnormalities in the anatomy, physiology, and function of medial temporal lobe structures in schizophrenia. Clinical similarities between schizophrenia and psychotic disorders associated with ...

August 1997

Limbic-cortical dysregulation: a proposed model of depression

Pages:471–481
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.471

Abstract
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A working model of depression implicating failure of the coordinated interactions of a distributed network of limbic-cortical pathways is proposed. Resting state patterns of regional glucose metabolism in idiopathic depressed patients, changes in ...

August 1997

The neurobiology of drug addiction

Pages:482–497
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.482

Abstract
PDF/EPUB

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Animals models have begun to provide insights into the neurobiological basis of reinforcement in drug addiction. The reinforcing effects of indirect sympathomimetics such as cocaine and amphetamine appear to depend on release of dopamine in the terminal ...

August 1997

The neural substrates of religious experience

Pages:498–510
Published Online:1 April 2006

https://doi.org/10.1176/jnp.9.3.498

Abstract
PDF/EPUB

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Religious experience is brain-based, like all human experience. Clues to the neural substrates of religious-numinous experience may be gleaned from temporolimbic epilepsy, near-death experiences, and hallucinogen ingestion. These brain disorders and ...

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