Clinical and Research ReportsFull Access
Use of Donepezil for Vascular Dementia
Preliminary Clinical Experience
Published Online:1 May 1999https://doi.org/10.1176/jnp.11.2.268
Abstract
The investigators evaluated donepezil, an acetylcholinesterase inhibitor, for vascular dementia. Eight outpatients with subcortical lesions and mild to moderate cognitive impairment received donepezil for 6 months. During this period, cognitive measures remained stable and caregivers reported improved patient activity, engagement, and self-care.
