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High phenylacetic acid differentiates schizoaffective from schizophrenic patients

Published Online:https://doi.org/10.1176/jnp.1.1.37

Twenty-four hour urinary phenylacetic acid was high in 12 acutely psychotic schizoaffective patients (240.3 +/- 51.9 mg/day) and low in 16 acutely psychotic schizophrenic patients (53.6 +/- 15.1 mg/day). These results indicate a biochemical difference between these two types of acute psychoses and indicate alterations in phenylalanine metabolism.

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