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Anticholinergic delirium caused by topical homatropine ophthalmologic solution: confirmation by anticholinergic radioreceptor assay in two cases

Published Online:https://doi.org/10.1176/jnp.4.2.195

The authors report two patients with prolonged metabolic delirium presumably initiated by systemic absorption of homatropine from a topical ophthalmologic solution. Anticholinergic toxicity was confirmed by muscarinic radioreceptor assay in both cases and by quantitative EEG in one case.

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