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Application of ictal brain SPECT for differentiating epileptic from nonepileptic seizures

Published Online:1 Apr 2006https://doi.org/10.1176/jnp.9.1.99

Abstract

The authors report 2 clinical cases that illustrate the difficulties with video-monitored EEG and the advantages of brain SPECT in differential diagnosis of true epileptic seizures and nonepileptic seizures. Injection of [99mTc]HMPAO at the time of the ictal event provides a means to obtain a SPECT image postictally for comparison with interictal examinations so that an epileptic or nonepileptic focus may be localized.