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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 30, Issue 1

January 2018

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Windows to the Brain

January 2018

The Habenula’s Role in Adaptive Behaviors: Contributions From Neuroimaging

Erica L. Epstein, Psy.D.,
Robin A. Hurley, M.D.,
Katherine H. Taber, Ph.D.

Pages:A4–4
Published Online:1 February 2018

https://doi.org/10.1176/appi.neuropsych.17110254

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Editorials

January 2018

Neuropsychiatry of Traumatic Brain Injury: A 30-Year Perspective

Jonathan M. Silver, M.D.

Pages:5–6
Published Online:1 February 2018

https://doi.org/10.1176/appi.neuropsych.17110337

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Special Articles

January 2018

Neurodegenerative Dementias After Traumatic Brain Injury

Christian LoBue, Ph.D.,
C. Munro Cullum, Ph.D.,
Nyaz Didehbani, Ph.D.,
Kylee Yeatman, B.S.,
Bruce Jones, Ph.D.,
Michael A. Kraut, M.D., Ph.D.,
John Hart, M.D.

Pages:7–13
Published Online:24 October 2017

https://doi.org/10.1176/appi.neuropsych.17070145

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Traumatic brain injury (TBI) is often considered to be a risk factor for the later development of neurodegenerative conditions, but some findings do not support a link. Differences in research methods, clinical samples, and limitations encountered when ...

January 2018

Noncognitive Behavioral Changes Associated With Alzheimer’s Disease: Implications of Neuroimaging Findings

Jeff Victoroff, M.D.
Feng V. Lin, Ph.D.
Kerry L. Coburn, Ph.D.,
Samuel D. Shillcutt, Pharm.D., Ph.D.,
Valerie Voon, M.D., Ph.D.,
Simon Ducharme, M.D., M.Sc.

Pages:14–21
Published Online:6 September 2017

https://doi.org/10.1176/appi.neuropsych.16080155

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Alzheimer’s disease (AD) is commonly associated with noncognitive behavioral changes (NCBCs). The authors systematically reviewed whether neuroimaging has helped with understanding the pathophysiology, diagnosis, or management of NCBCs associated with AD, ...

January 2018

The Anterior Temporal Lobes: New Frontiers Opened to Neuropsychological Research by Changes in Health Care and Disease Epidemiology

Guido Gainotti, M.D.

Pages:22–30
Published Online:4 August 2017

https://doi.org/10.1176/appi.neuropsych.17010002

Abstract
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Changes in health care and disease epidemiology have shifted the attention of neuropsychologists and cognitive neuroscientists from vascular lesions to degenerative diseases or other bilateral brain lesions. This displacement of attention from vascular ...

Regular Articles

January 2018

Dyslexic Characteristics of Chinese-Speaking Semantic Variant of Primary Progressive Aphasia

Simon Kang Seng Ting, M.D.,
Heidi Foo, B.Psych.,
Pei Shi Chia, B.Sc. (Hons.),
Shahul Hameed, M.D.,
Kok Pin Ng, M.D.,
Adeline Ng, M.D.,
Nagaendran Kandiah, M.D.

Pages:31–37
Published Online:24 October 2017

https://doi.org/10.1176/appi.neuropsych.17040081

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Reading disorder is a recognized feature in primary progressive aphasia (PPA). Surface dyslexia, characterized by regularization errors, is typically seen in the English-speaking semantic variant of PPA (svPPA). However, dyslexic characteristics of other ...

January 2018

Use of the Neuropsychiatric Inventory to Characterize the Course of Neuropsychiatric Symptoms in Progressive Supranuclear Palsy

Milica Ječmenica-Lukić, M.D.,
Tatjana Pekmezović, M.D., Ph.D.,
Igor N. Petrović, M.D., Ph.D.,
Aleksandra Tomić, M.D.,
Marina Svetel, M.D., Ph.D.,
Vladimir S. Kostić, M.D., Ph.D.

Pages:38–44
Published Online:16 May 2017

https://doi.org/10.1176/appi.neuropsych.17010012

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The aim of this study was to determine the neuropsychiatric profile in a cohort of progressive supranucelar palsy (PSP) patients and their dynamic changes over a follow-up period of 1 year. A total of 59 patients were assessed at baseline, while 25 of ...

January 2018

Glucocorticoid Receptor Genetic Variants and Response to Fluoxetine in Major Depressive Disorder

Hasti Nouraei, B.S.,
Negar Firouzabadi, Ph.D.,
Ali Mandegary, Ph.D.,
Kamiar Zomorrodian, Ph.D.,
Ehsan Bahramali, M.D.,
Mohammad Reza Hooshangi Shayesteh, M.S.,
Saham Ansari, Ph.D.

Pages:45–50
Published Online:23 June 2017

https://doi.org/10.1176/appi.neuropsych.16120322

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Hyperactivity of the hypothalamic pituitary adrenocortical (HPA) axis is one of the main clinical findings in depression. The HPA axis is interrelated with glucocorticoid signaling via glucocorticoid receptors (GCRs). Thus, functional genetic variants on ...

Education in Behavioral Neurology & Neuropsychiatry

January 2018

Responding to Ten Common Delirium Misconceptions With Best Evidence: An Educational Review for Clinicians

Mark A. Oldham, M.D.,
Nina M. Flanagan, Ph.D.,
Ariba Khan, M.D., M.P.H.,
Olga Boukrina, Ph.D.,
Edward R. Marcantonio, M.D., M.Sc.

Pages:51–57
Published Online:6 September 2017

https://doi.org/10.1176/appi.neuropsych.17030065

Abstract
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Delirium (acute confusion) is a serious, common health condition, and it predicts poor outcomes, including greater rates of mortality, institutionalization, prolonged hospitalization, and cognitive impairment. Expedient diagnosis and management are ...

Clinical and Research Reports

January 2018

A Neuropsychiatric Analysis of the Cotard Delusion

Aradhana Sahoo, B.S.,
Keith A. Josephs, M.D.

Pages:58–65
Published Online:23 June 2017

https://doi.org/10.1176/appi.neuropsych.17010018

Abstract
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Cotard’s syndrome, a condition in which the patient denies his or her own existence or the existence of body parts, is a rare illness that has been reported in association with several neuropsychiatric diagnoses. The majority of published literature on ...

January 2018

Guanfacine Attenuates Adverse Effects of Dronabinol (THC) on Working Memory in Adolescent-Onset Heavy Cannabis Users: A Pilot Study

David S. Mathai, M.D.,
Manuela Holst, Ph.D.,
Christopher Rodgman, M.D.,
Colin N. Haile, M.D., Ph.D.,
Jake Keller, B.S.,
Mariyah Z. Hussain, M.D.,
Thomas R. Kosten, M.D.,
Thomas F. Newton, M.D.,
Christopher D. Verrico, Ph.D.

Pages:66–76
Published Online:23 June 2017

https://doi.org/10.1176/appi.neuropsych.16120328

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The cannabinoid-1 receptor (CB1R) agonist Δ9-tetrahydrocannabinol (THC), the main psychoactive constituent of cannabis, adversely effects working memory performance in humans. The α2A-adrenoceptor (AR) agonist guanfacine improves working memory ...

January 2018

Overload From Anxiety: A Non-Motor Cause for Gait Impairments in Parkinson’s Disease

Kaylena A. Ehgoetz Martens, Ph.D.,
Carolina R.A. Silveira, Ph.D.,
Brittany N. Intzandt, M.Sc.,
Quincy J. Almeida, Ph.D.

Pages:77–80
Published Online:17 July 2017

https://doi.org/10.1176/appi.neuropsych.16110298

Abstract
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Threatening situations lead to observable gait deficits in individuals with Parkinson’s disease (PD) who suffer from high trait anxiety levels. The specific characteristics of gait that are affected appear to be similar to behaviors observed while walking ...

Case Reports

January 2018

Anterior Cerebral Artery Territory Infarction-Related Resolution of Chronic Lower Back Pain

Christopher M. Filley, M.D.,
Haley Burke, M.D.,
C. Alan Anderson, M.D.

Pages:81–83
Published Online:17 July 2017

https://doi.org/10.1176/appi.neuropsych.17040080

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January 2018

Pseudo-Charles Bonnet Syndrome With a Frontal Tumor: Visual Hallucinations, the Brain, and the Two-Hit Hypothesis

Katherine A. Kosman, M.D., M.B.A.,
David A. Silbersweig, M.D.

Pages:84–86
Published Online:4 August 2017

https://doi.org/10.1176/appi.neuropsych.17040076

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