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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 28, Issue 3

July 2016

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Windows to the Brain

July 2016

Update on Obstructive Sleep Apnea: Implications for Neuropsychiatry

Christopher A. Baker, Psy.D.,
Robin A. Hurley, M.D,
Katherine Taber, Ph.D.

Pages:A6–159
Published Online:22 July 2016

https://doi.org/10.1176/appi.neuropsych.16060115

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Editorial

July 2016

Delusional Misidentification Syndromes: Progress and New Challenges

C. Alan Anderson, M.D., and
Christopher M. Filley, M.D.

Pages:160–161
Published Online:22 July 2016

https://doi.org/10.1176/appi.neuropsych.16030055

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Special Articles

July 2016

Pathological Joking or Witzelsucht Revisited

Elias D. Granadillo, M.D., and
Mario F. Mendez, M.D., Ph.D.

Pages:162–167
Published Online:22 February 2016

https://doi.org/10.1176/appi.neuropsych.15090238

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Humor, or the perception or elicitation of mirth and funniness, is distinguishable from laughter and can be differentially disturbed by neuropsychiatric disease. The authors describe two patients with constant joking, or Witzelsucht, in the absence of ...

July 2016

Functional Neuroanatomy and Neurophysiology of Functional Neurological Disorders (Conversion Disorder)

Valerie Voon, M.D., Ph.D.,
Andrea E. Cavanna, M.D., Ph.D.,
Kerry Coburn, Ph.D.,
Shirlene Sampson, M.D.,
Alya Reeve, M.D.,
W. Curt LaFrance, M.D.
(On behalf of the American Neuropsychiatric Association Committee for Research)

Pages:168–190
Published Online:22 February 2016

https://doi.org/10.1176/appi.neuropsych.14090217

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Much is known regarding the physical characteristics, comorbid symptoms, psychological makeup, and neuropsychological performance of patients with functional neurological disorders (FNDs)/conversion disorders. Gross neurostructural deficits do not account ...

Regular Articles

July 2016

Apathy Is Associated With Ventral Striatum Volume in Schizophrenia Spectrum Disorder

Robert M. Roth, Ph.D.,
Matthew A. Garlinghouse, Ph.D.,
Laura A. Flashman, Ph.D.,
Nancy S. Koven, Ph.D.,
J. Cara Pendergrass, Ph.D.,
James C. Ford, Ph.D.,
Thomas W. McAllister, M.D.,
Andrew J. Saykin, Psy.D.

Pages:191–194
Published Online:22 February 2016

https://doi.org/10.1176/appi.neuropsych.15100241

Abstract
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Apathy is prevalent in schizophrenia, but its etiology has received little investigation. The ventral striatum (VS), a key brain region involved in motivated behavior, has been implicated in studies of apathy. We therefore evaluated whether apathy is ...

July 2016

Psychogenic Ophthalmologic Movement Disorders

José Fidel Baizabal-Carvallo, M.D., M.Sc., and
Joseph Jankovic, M.D.

Pages:195–198
Published Online:21 January 2016

https://doi.org/10.1176/appi.neuropsych.15050104

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In this study, the authors retrospectively identified 11 patients with psychogenic ophthalmologic movement disorders (POMDs) (6%) among 182 patients with psychogenic movement disorders (PMDs), using medical charts and video reviews. The phenomenology ...

July 2016

Quantifying Poststroke Apathy With Actimeters

Andrew M. Goldfine, M.D., M.Sc.,
Behdad Dehbandi, M.Sc.,
Juliana M. Kennedy, B.S.,
Briana Sabot,
Cory Semper, M.E.,
David Putrino, Ph.D., P.T.

Pages:199–204
Published Online:22 February 2016

https://doi.org/10.1176/appi.neuropsych.15090235

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The authors tested the hypothesis that wrist-worn actimeters can quantify the severity of poststroke apathy. The authors studied 57 patients admitted to an acute rehabilitation unit for ischemic or hemorrhagic stroke. After accounting for motor deficit of ...

July 2016

Psychiatric Symptoms in the Initial Motor Stage of Parkinson's Disease

Iva Stanković, M.D.,
Elka Stefanova, M.D., Ph.D.,
Aleksandra Tomić, M.D.,
Milica Ječmenica Lukić, M.D.,
Tanja Stojković, M.D.,
Vladana Marković, M.D.,
Gorana Mandić Stojmenović, M.D.,
Nikola Kresojević, M.D.,
Marina Svetel, M.D., Ph.D.,
Vladimir Kostić, M.D., Ph.D.

Pages:205–210
Published Online:22 February 2016

https://doi.org/10.1176/appi.neuropsych.15100244

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Neuropsychiatric symptoms (NPS) are common in Parkinson’s disease (PD). The aim of this study was to estimate the correlates of NPS in patients with PD in the initial motor stage of the disease (hemiparkinsonism). A total of 111 patients with PD and 105 ...

July 2016

Mood Differences Among Parkinson’s Disease Patients With Mild Cognitive Impairment

Jacob D. Jones, M.S.,
Paul Mangal, M.S.,
Jacob Lafo, M.S.,
Michael S. Okun, M.D.,
Dawn Bowers, Ph.D.

Pages:211–216
Published Online:21 January 2016

https://doi.org/10.1176/appi.neuropsych.15090221

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Studies with healthy elderly adults suggest that apathy, depression, and anxiety are more common among individuals with mild cognitive impairment (MCI). This study examined differences in mood/amotivational symptoms among patients with Parkinson’s disease ...

July 2016

Lesion-Related Delusional Misidentification Syndromes: A Comprehensive Review of Reported Cases

Ryan Darby, M.D., and
Sashank Prasad, M.D.

Pages:217–222
Published Online:22 February 2016

https://doi.org/10.1176/appi.neuropsych.15100376

Abstract
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Delusional misidentification syndromes (DMSs) are persistent delusions of hyper- or hypofamiliarity for meaningful persons and places in one's environment. This study set to determine the clinical course, neuroanatomical localization, neuropsychological ...

July 2016

Saccadic Impairment Associated With Remote History of Mild Traumatic Brain Injury

Mark L. Ettenhofer, Ph.D., and
David M. Barry, Ph.D.

Pages:223–231
Published Online:28 March 2016

https://doi.org/10.1176/appi.neuropsych.15100243

Abstract
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Evidence suggests that mild traumatic brain injury (TBI) is associated with long-term changes in brain function, but conventional neurocognitive tools are often insensitive to deficits after 90 days. Eye movements have been proposed as a means to identify ...

Clinical and Research Reports

July 2016

Deficits in Limb Praxis in Patients With Obsessive-Compulsive Disorder

Elisabeth Rounis, M.D., Ph.D.,
Paula Banca, Ph.D.,
Valerie Voon, M.D., Ph.D.

Pages:232–235
Published Online:21 January 2016

https://doi.org/10.1176/appi.neuropsych.15090233

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There is recent evidence of deficits in praxis in patients with primary dystonia. Obsessive-compulsive disorder (OCD) has been linked to disorders of higher-order motor function, such as dystonia. However, no clear mechanism underlying such a relationship ...

July 2016

Exploring the Structural Relationship Between Interviewer and Self-Rated Affective Symptoms in Huntington’s Disease

John Maltby, D.Phil.,
Maria Dale, D.Clin.Psy.,
Mandy Underwood, D.Clin.Psy.,
Hugh Rickards, M.D.,
Jenny Callaghan, B.Sc., and
REGISTRY Investigators of the European Huntington’s Disease Network

Pages:236–238
Published Online:22 February 2016

https://doi.org/10.1176/appi.neuropsych.15090237

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This study explores the structural relationship between self-report and interview measures of affect in Huntington’s disease. The findings suggest continued use of both to recognize the multidimensionality within a single common consideration of distress.

July 2016

Psychiatric Comorbidities in Restless Legs Syndrome

Ulf Kallweit, M.D.,
Esther Werth, Ph.D.,
Angela Seiz, M.S.,
Sandra Sefidan, M.S.,
Norbert Dahmen, M.D., Prof.,
Mauro Manconi, M.D., Ph.D.,
Ulrike Ehlert, M.S., Ph.D., Prof.,
Claudio L.A. Bassetti, M.D., Prof.

Pages:239–242
Published Online:28 March 2016

https://doi.org/10.1176/appi.neuropsych.15030055

Abstract
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Restless legs syndrome (RLS) is a neurological sleep disorder with frequent (39%) coexisting psychiatric comorbidities. Patients with any psychiatric comorbidity had fewer periodic leg movements in sleep. Psychiatric disorders should be taken into account ...

July 2016

The Effect of Intravenous Citalopram on the Neural Substrates of Obsessive-Compulsive Disorder

Tracy P. Bhikram, M.Sc.,
Norman A.S. Farb, Ph.D.,
Lakshmi N. Ravindran, M.D., F.R.C.P.C.,
Yousef G. Papadopoulos, M.D., F.R.C.P.C.,
David K. Conn, M.B., F.R.C.P.C.,
Bruce G. Pollock, M.D., Ph.D., F.R.C.P.C.,
Arun V. Ravindran, M.D., Ph.D., F.R.C.P.C.

Pages:243–247
Published Online:28 March 2016

https://doi.org/10.1176/appi.neuropsych.15090213

Abstract
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This study investigated the effect of an intravenous serotonin reuptake inhibitor on the neural substrates of obsessive-compulsive disorder (OCD), as intravenous agents may be more effective in treating OCD than conventional oral pharmacotherapy. Eight ...

Book Review

July 2016

Translational Neuroscience: Toward New Therapies

Eric Gausche, M.D.

Page:248
Published Online:22 July 2016

https://doi.org/10.1176/appi.neuropsych.16010008

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Abstracts

July 2016

2016 American Neuropsychiatric Association Annual Meeting Abstracts

Pages:e33–e66
Published Online:22 July 2016

https://doi.org/10.1176/appi.neuropsych.15080210

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Letters to the Editor

July 2016

Capgras Syndrome and Phantom Vest Following Traumatic Brain Injury

Melissa Jones, M.D.,
Joanne A. Byars, M.D.,
Manuel Mas-Rodriguez, M.D.,
David B. Arciniegas, M.D.

Pages:253–254
Published Online:22 July 2016

https://doi.org/10.1176/appi.neuropsych.15120418

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July 2016

The Neurocognitive Profile of an Anti-N-Methyl-D-Aspartate Receptor Encephalitis Patient Presenting With Neuropsychiatric Symptoms

Cristina Parfene, Psy.D.,
Cecilia Lipira, M.D.,
Faith Gunning, Ph.D.,
Janna S. Gordon-Elliott, M.D.

Pages:255–256
Published Online:22 July 2016

https://doi.org/10.1176/appi.neuropsych.16020026

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