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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 33, Issue 1

January 2021

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Tribute

January 2021

A Tribute to Katherine H. Taber, Ph.D., F.A.N.P.A.

Robin A. Hurley, M.D., F.A.N.P.A.

Pages:1–2
Published Online:21 January 2021

https://doi.org/10.1176/appi.neuropsych.20120299

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Special Articles

January 2021

Drug Development for Psychotropic, Cognitive-Enhancing, and Disease-Modifying Treatments for Alzheimer’s Disease

Jeffrey Cummings, M.D., Sc.D.

Pages:3–13
Published Online:28 October 2020

https://doi.org/10.1176/appi.neuropsych.20060152

Abstract
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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with limited available therapies. There is progress in developing treatments for neuropsychiatric indications in AD, including agitation, psychosis, apathy, and sleep disorders. ...

January 2021

A Review and Expert Opinion on the Neuropsychiatric Assessment of Motor Functional Neurological Disorders

David L. Perez, M.D., M.M.Sc.,
Selma Aybek, M.D.,
Stoyan Popkirov, M.D.,
Kasia Kozlowska, M.B.B.S., Ph.D.,
Christopher D. Stephen, M.B.Ch.B., M.R.C.P.,
Jordan Anderson, D.O.,
Robert Shura, Psy.D., A.B.P.P.,
Simon Ducharme, M.D., M.Sc.,
Alan Carson, M.D., Ph.D.,
Mark Hallett, M.D.,
Timothy R. Nicholson, M.D., Ph.D.,
Jon Stone, Ph.D., F.R.C.P.,
W. Curt LaFrance, M.D., M.P.H.,
Valerie Voon, M.D., Ph.D.,
(On behalf of the American Neuropsychiatric Association Committee for Research)

Pages:14–26
Published Online:11 August 2020

https://doi.org/10.1176/appi.neuropsych.19120357

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Functional neurological (conversion) disorder (FND) is a prevalent and disabling condition at the intersection of neurology and psychiatry. Advances have been made in elucidating an emerging pathophysiology for motor FND, as well as in identifying ...

January 2021

Evidence-Based Practice for the Clinical Assessment of Psychogenic Nonepileptic Seizures: A Report From the American Neuropsychiatric Association Committee on Research

Gaston Baslet, M.D.,
Sepideh N. Bajestan, M.D., Ph.D.,
Selma Aybek, M.D.,
Mandana Modirrousta, M.D., Ph.D.,
Jason Price D.Clin.Psy.,
Andrea Cavanna, M.D., Ph.D.,
David L. Perez, M.D.,
Shelby Scott Lazarow, Psy.D.,
Geoffrey Raynor, M.D.,
Valerie Voon, M.D., Ph.D.,
Simon Ducharme, M.D., M.Sc.,
W. Curt LaFrance, M.D., M.P.H.

Pages:27–42
Published Online:11 August 2020

https://doi.org/10.1176/appi.neuropsych.19120354

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The American Neuropsychiatric Association’s Committee on Research assigned the task of defining the most helpful clinical factors and tests in establishing the diagnosis of psychogenic nonepileptic seizures (PNES) during a neuropsychiatric assessment. A ...

Regular Articles

January 2021

Effective Tools to Predict Depression in Acute and Subacute Phase of Ischemic Stroke

Katsunaka Mikami, M.D., Ph.D.,
Takeshi Sudo, Ph.D.,
Yasushi Orihashi, M.S.,
Keitaro Kimoto, M.D.,
Atsushi Mizuma, M.D., Ph.D.,
Tsuyoshi Uesugi, M.D., Ph.D.,
Reina Kawamura, M.D.,
Kazunari Honma, M.D.,
Eiichiro Nagata, M.D., Ph.D.,
Kenji Yamamoto, M.D., Ph.D.,
Shunya Takizawa, M.D., Ph.D.,
Hideo Matsumoto, M.D., Ph.D.,
Robert G. Robinson, M.D.

Pages:43–48
Published Online:22 October 2020

https://doi.org/10.1176/appi.neuropsych.20040076

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Objective:Despite the high frequency of depression in the first year following stroke, few studies have predicted risk of depression after the acute and subacute stroke periods. The aim of this study was to identify, in the acute and subacute periods, ...

January 2021

Associations Between Neuroanatomic Patterns of Cerebral Infarctions and Vascular Dementia

Emre Kumral, M.D.,
Fatma Ece Bayam, M.D.,
Hasan Arslan, Ph.D.,
Mehmet Orman, M.D., Ph.D.

Pages:49–56
Published Online:28 July 2020

https://doi.org/10.1176/appi.neuropsych.19120356

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Objective:A history of multiple cerebral infarctions is generally regarded as an important risk factor for vascular dementia. The authors examined the risk of vascular dementia in patients with multiple acute ischemic lesions.Methods:The authors conducted ...

January 2021

The Patient Experience of Recovery Following Anti-NMDA Receptor Encephalitis: A Qualitative Content Analysis

Gemma McKeon, D.Psych.,
Stephen Parker, Ph.D., M.B.B.S.,
Nicola Warren, M.B.B.S.,
James G. Scott, Ph.D., M.B.B.S.

Pages:57–63
Published Online:2 September 2020

https://doi.org/10.1176/appi.neuropsych.20030049

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Objective:The authors examined patients’ perceptions of the factors affecting their recovery from anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis, which is a rare, severe immune-mediated neurological disorder.Methods:Seven patients completed ...

January 2021

Association of Cortical and Subcortical β-Amyloid With Standardized Measures of Depressive and Anxiety Symptoms in Adults Without Dementia

Janina Krell-Roesch, Ph.D.,
Jeremy A. Syrjanen, M.S.,
Martin Rakusa, M.D.,
Prashanthi Vemuri, Ph.D.,
Mary M. Machulda, Ph.D., L.P.,
Walter K. Kremers, Ph.D.,
Michelle M. Mielke, Ph.D.,
Val J. Lowe, M.D.,
Clifford R. Jack, M.D.,
David S. Knopman, M.D.,
Gorazd B. Stokin, M.D., Ph.D.,
Ronald C. Petersen, M.D., Ph.D,
Maria Vassilaki, M.D., Ph.D,
Yonas E. Geda, M.D., M.Sc.

Pages:64–71
Published Online:22 October 2020

https://doi.org/10.1176/appi.neuropsych.20050103

Abstract
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Objective:The purpose of this study was to test the hypothesis that subcortical β-amyloid (Aβ) deposition was associated with elevated scores on standardized measures of depressive and anxiety symptoms when compared with cortical (Aβ) deposition in ...

January 2021

The Functionality, Evidence, and Privacy Issues Around Smartphone Apps for the Top Neuropsychiatric Conditions

Mia T. Minen, M.D., M.P.H.,
Ariana Gopal, B.S.,
Gabriella Sahyoun,
Eric Stieglitz, J.D.,
John Torous, M.D.

Pages:72–79
Published Online:16 July 2020

https://doi.org/10.1176/appi.neuropsych.19120353

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Objective:There are more than 325,000 health-related smartphone applications (apps) on the market. To better understand the apps currently on the market for the five most disabling neuropsychiatric conditions, the authors conducted a study investigating ...

Clinical and Research Reports

January 2021

Presymptomatic Testing and Confidentiality in the Age of the Electronic Medical Record

Kevin J. Black, M.D., F.A.N.P.A.,
Stacey K. Barton, M.S.W., L.C.S.W.,
Joel S. Perlmutter, M.D.

Pages:80–83
Published Online:16 July 2020

https://doi.org/10.1176/appi.neuropsych.20030068

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Objective:Recent introduction of a commercial electronic medical record (EMR) system at the authors’ institution raised a number of questions about documenting visits for presymptomatic testing for Huntington’s disease (HD). Specifically, adoption of the ...

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