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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 33, Issue 2

May 2021

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WINDOWS TO THE BRAIN

May 2021

Sexual Dimorphism in Brain Development: Influence on Affective Disorders

Wilfredo López-Ojeda, Ph.D., M.S.,
Robin A. Hurley, M.D.

Pages:A4, 85–89
Published Online:21 May 2021

https://doi.org/10.1176/appi.neuropsych.20100269

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Articles

May 2021

Cognitive, Graphomotor, and Psychosocial Challenges in Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS)

Mary K. Colvin, Ph.D.,
Savannah Erwin, M.A.,
Priyanka R. Alluri, B.A.,
Alexandra Laffer, M.A.,
Kathryn Pasquariello, B.S.,
Kyle A. Williams, M.D., Ph.D.

Pages:90–97
Published Online:2 December 2020

https://doi.org/10.1176/appi.neuropsych.20030065

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Objectives: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) is characterized by the sudden onset of obsessive-compulsive disorder (OCD) and other neurobehavioral symptoms following group A streptococcal ...

May 2021

Independent and Synergistic Associations Between TBI Characteristics and PTSD Symptom Clusters on Cognitive Performance and Postconcussive Symptoms in Iraq and Afghanistan Veterans

Sarah M Jurick, Ph.D.,
Laura D. Crocker, Ph.D.,
Victoria C. Merritt, Ph.D.,
Mark E. Sanderson-Cimino, M.S.,
Amber V. Keller, B.A.,
Lisa H. Glassman, Ph.D.,
Elizabeth W. Twamley, Ph.D.,
Carie S. Rodgers, Ph.D.,
Dawn M. Schiehser, Ph.D.,
Robin L. Aupperle, Ph.D.,
Amy J. Jak, Ph.D.

Pages:98–108
Published Online:14 January 2021

https://doi.org/10.1176/appi.neuropsych.20050128

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Objective: The investigators sought to evaluate the independent and interactive associations between mild traumatic brain injury (mTBI) characteristics and posttraumatic stress disorder (PTSD) symptoms with regard to postconcussive symptoms and cognition ...

May 2021

History of Functional Somatic Syndromes and Persistent Symptoms After Mild Traumatic Brain Injury

Katherine Green, M.Sc.,
Molly Cairncross, Ph.D.,
William J. Panenka, M.D.,
Jacob L. Stubbs, B.Kin.,
Noah D. Silverberg, Ph.D.

Pages:109–115
Published Online:18 November 2020

https://doi.org/10.1176/appi.neuropsych.20060159

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Objective: Somatization is thought to underlie functional somatic syndromes (FSSs) and may also contribute to prolonged symptoms after mild traumatic brain injury (mTBI). The investigators evaluated the prevalence of FSSs in patients seeking specialty ...

May 2021

Correlation Between Rostral Dorsomedial Prefrontal Cortex Activation by Trauma-Related Words and Subsequent Response to CBT for PTSD

Daniel Weisholtz, M.D.,
David Silbersweig, M.D.,
Hong Pan, Ph.D.,
Marylene Cloitre, Ph.D,
Joseph LeDoux, Ph.D.,
Emily Stern, M.D.

Pages:116–123
Published Online:28 October 2020

https://doi.org/10.1176/appi.neuropsych.20030058

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Objective: Trauma-focused cognitive-behavioral therapy (CBT) is an important component of evidence-based treatment for posttraumatic stress disorder (PTSD), but the efficacy of treatment varies from individual to individual. It is hypothesized that some ...

May 2021

The Profile and Evolution of Neuropsychiatric Symptoms in Multiple System Atrophy: Self- and Caregiver Report

Milica Jecmenica-Lukic, M.D., Ph.D.,
Igor N. Petrovic, M.D., Ph.D.,
Tatjana Pekmezovic, M.D., Ph.D.,
Aleksandra Tomic, M.D., Ph.D.,
Iva Stankovic, M.D.,
Marina Svetel, M.D., Ph.D.,
Vladimir S. Kostic, M.D., Ph.D.

Pages:124–131
Published Online:2 December 2020

https://doi.org/10.1176/appi.neuropsych.20030057

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Objective: Recent research shows that patients with multiple system atrophy (MSA) have significant cognitive and neuropsychiatric comorbidities that can color the clinical presentation of the disease and affect their quality of life. The aims of this ...

May 2021

Depression, Anxiety, Stress, and Health-Related Quality of Life Among Patients With Medication Overuse Headache in a Tertiary Headache Center: A Cross-Sectional Study

Marina Ljubisavljevic, M.Sc.,
Aleksandra Ignjatovic, M.D., Ph.D.,
Vladimir Djordjevic, M.D., Ph.D.,
Marina Hadzi Pesic, M.Sc., Ph.D.,
Srdjan Ljubisavljevic, M.D., Ph.D

Pages:132–143
Published Online:25 February 2021

https://doi.org/10.1176/appi.neuropsych.20070189

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Objective: The investigators examined the association of patient-related and headache-related parameters and the effect of medication overuse headache (MOH); the occurrence of depression, anxiety, and stress; and the importance of different domains of ...

May 2021

Association of Preoperative Visual Hallucinations With Cognitive Decline After Deep Brain Stimulation for Parkinson’s Disease

Ian H. Kratter, M.D., Ph.D.,
Jordan F. Karp, M.D.,
Yue-Fang Chang, Ph.D.,
Ashley C. Whiteman,
Michael T. Feyder, Ph.D.,
Ahmed Jorge, M.D., Ph.D.,
R. Mark Richardson, M.D., Ph.D.,
Luke C. Henry, Ph.D.

Pages:144–151
Published Online:18 November 2020

https://doi.org/10.1176/appi.neuropsych.20040077

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Objective: Deep brain stimulation (DBS) is effective for the motor symptoms of Parkinson’s disease (PD). Although most patients benefit with minimal cognitive side effects, cognitive decline is a risk, and there is little available evidence to guide ...

Analysis and Commentary

May 2021

Distinguishing Behavioral Variant Frontotemporal Dementia From Primary Psychiatric Disorders: A Review of Recently Published Consensus Recommendations From the Neuropsychiatric International Consortium for Frontotemporal Dementia

Peter S. Pressman, M.D.,
Daniel Matlock, M.D.,
Simon Ducharme, M.D.

Pages:152–156
Published Online:14 January 2021

https://doi.org/10.1176/appi.neuropsych.20090238

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The behavioral variant of frontotemporal dementia (bvFTD) is the second most common cause of dementia for individuals <65 years old, but accurate diagnosis is often delayed for several years. While previous criteria have increased the ability of ...

May 2021

Frontotemporal Dementia: A Window to Alexithymia

Mario F. Mendez, M.D., Ph.D.

Pages:157–160
Published Online:4 February 2021

https://doi.org/10.1176/appi.neuropsych.20100252

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Alexithymia is pervasive among psychiatric patients, but its neurobiological mechanism is unclear. Patients with alexithymia cannot “read emotions,” a process involving interoception, or the perception of the body’s internal state, primarily in the ...

Clinical and Research Reports

May 2021

Psychiatric, Motor, and Autonomic Effects of Bifrontal ECT in Depressed Parkinson’s Disease Patients

Isaac Rodin, B.Sc.,
Je Hun Sung, M.D.,
Silke Appel-Cresswell, M.D., F.R.C.P.C.,
Harpreet Chauhan, M.D., F.R.C.P.C.,
Kevin Smith, M.D., F.R.C.P.C.,
Fidel Vila-Rodriguez, M.D., Ph.D.,
Nicholas J. Ainsworth, M.D., F.R.C.P.C.

Pages:161–166
Published Online:25 February 2021

https://doi.org/10.1176/appi.neuropsych.20050133

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Objective: Depressive symptoms are a source of significant morbidity in Parkinson’s disease (PD). Electroconvulsive therapy (ECT) is a promising treatment for depression in PD (dPD); however, data remain limited, including data on optimal electrode ...

Case Reports

May 2021

Deep Brain Stimulation for OCD in a Patient With Comorbidities: Epilepsy, Tics, Autism, and Major Depressive Disorder

Rachel A. Davis, M.D.,
Helena Winston, M.D.,
Judith M. Gault, Ph.D.,
Drew S. Kern, M.D., M.S.,
Susan K. Mikulich-Gilbertson, Ph.D.,
Aviva Abosch, M.D., Ph.D.

Pages:167–171
Published Online:4 February 2021

https://doi.org/10.1176/appi.neuropsych.20060153

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