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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 33, Issue 4

October 2021

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Windows to the Brain

October 2021

Enigmatic Neural Pathways: Potentiating Viral Neuroinvasion Into the CNS

Wilfredo López-Ojeda, M.S., Ph.D.,
Robin A. Hurley, M.D.

Pages:260–265
Published Online:28 October 2021

https://doi.org/10.1176/appi.neuropsych.21060152

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Special Articles

October 2021

COVID-19 Infection: A Neuropsychiatric Perspective

Theodora A. Manolis, M.D.,
Evdoxia J. Apostolopoulos, B.Sc.,
Antonis A. Manolis, M.S., B.Sc.,
Helen Melita, M.D.,
Antonis S. Manolis, M.D.

Pages:266–279
Published Online:19 July 2021

https://doi.org/10.1176/appi.neuropsych.20110277

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As a potentially life-threatening disease with no definitive treatment and without fully implemented population-wide vaccination, COVID-19 has created unprecedented turmoil in socioeconomic life worldwide. In addition to physical signs from the ...

October 2021

Anxiety in Parkinson’s Disease: A Systematic Review of Neuroimaging Studies

Kate Perepezko, M.S.P.H.,
Farah Naaz, Ph.D.,
Carrie Wagandt,
Nadeeka N. Dissanayaka, Ph.D.,
Zoltan Mari, M.D.,
Julie Nanavati, M.L.S., M.A.,
Arnold Bakker, Ph.D.,
Gregory M. Pontone, M.D., M.H.S.

Pages:280–294
Published Online:19 July 2021

https://doi.org/10.1176/appi.neuropsych.20110272

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Objective:The mechanisms and neuronal networks associated with anxiety in Parkinson’s disease (PD) are incompletely understood. One of the best tools for investigating both component function and neuronal networks associated with psychiatric symptoms is ...

October 2021

Understanding Psychiatric Disorders in Idiopathic and Inherited (Monogenic) Forms of Isolated and Combined Dystonia: A Systematic Review

Victoria Lane, M.B.Ch.B. (Hons.), M.R.C.Psych.,
Mark Lane, M.B.B.S. (Hons.), F.R.C.Opth.,
Aaron Sturrock, M.R.C.P., M.D. (Res.),
Hugh Rickards, F.R.C.Psych., M.D.

Pages:295–306
Published Online:19 July 2021

https://doi.org/10.1176/appi.neuropsych.20110293

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Objective:The relationship between idiopathic and inherited (monogenic) forms of isolated and combined dystonia and psychiatric disorders remains unclear. In the present review, the authors aimed to provide increased clarity on this association through a ...

October 2021

Cognitive Control Deficits in Depression: A Novel Target to Improve Suboptimal Outcomes in Childhood

Jane S. Oliveira, Psy.D.,
Madeline C. Manning, M.A.,
Brian C. Kavanaugh, Psy.D.

Pages:307–313
Published Online:15 July 2021

https://doi.org/10.1176/appi.neuropsych.20090236

Abstract
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Cognitive control deficits are one of three primary endophenotypes in depression, and the enhanced targeting of these deficits in clinical and research work is expected to lead to improved depression outcomes. Cognitive control is a set of self-regulatory ...

Regular Articles

October 2021

Elevated Mood States in Patients With Parkinson’s Disease Treated With Deep Brain Stimulation: Diagnosis and Management Strategies

Andreea L. Seritan, M.D.,
Lauren L. Spiegel, M.D.,
Jessica L. Weinstein, M.D.,
Caroline A. Racine, Ph.D.,
Ethan G. Brown, M.D.,
Monica Volz, N.P.,
Coralie de Hemptinne, Ph.D.,
Philip A. Starr, M.D., Ph.D.,
Jill L. Ostrem, M.D.

Pages:314–320
Published Online:2 July 2021

https://doi.org/10.1176/appi.neuropsych.20080205

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Objective:Deep brain stimulation (DBS) is an effective surgical treatment for patients with Parkinson’s disease (PD). DBS therapy, particularly with the subthalamic nucleus (STN) target, has been linked to rare psychiatric complications, including ...

October 2021

Neurobiological and Psychosocial Correlates of Communication Between Huntington’s Disease Patients and Their Offspring

Kelly H. Watson, Ph.D.,
Abagail E. Ciriegio, M.Ed.,
Anna C. Pfalzer, Ph.D.,
Lisa Hale, L.M.S.W.,
Maile T. Jones, M.Ed.,
Brittany Brown, B.S.,
Victoria Grice, B.A.,
Sarah Moroz, B.A., M.P.H.,
Katherine E. McDonell, M.D.,
Daniel O. Claassen, M.D.,
Bruce E. Compas, Ph.D.

Pages:321–327
Published Online:19 July 2021

https://doi.org/10.1176/appi.neuropsych.20120309

Abstract
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Objective:Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease that presents significant challenges to family communication. The investigators examined observations of communication between parents with HD and their offspring ...

October 2021

A Phase-2 Pilot Study of a Therapeutic Combination of Δ⁹-Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette’s Syndrome

Michael H. Bloch, M.D., M.S.,
Angeli Landeros-Weisenberger, M.D.,
Jessica A. Johnson, B.A.,
James F. Leckman, M.D., Ph.D.

Pages:328–336
Published Online:3 August 2021

https://doi.org/10.1176/appi.neuropsych.19080178

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Objective:There are few effective pharmacological treatments for Tourette’s syndrome. Many patients with Tourette’s syndrome experience impairing tic symptoms despite use of available evidence-based treatments. The investigators conducted a small, ...

Clinical and Research Reports

October 2021

Resting-State Correlations of Fatigue Following Military Deployment

Jeffrey D. Lewis, Ph.D., M.D.,
Kristine M. Knutson, M.A.,
Stephen J. Gotts, Ph.D.,
Michael Tierney, M.A.,
Amy Ramage, Ph.D.,
David F. Tate, Ph.D.,
Daniel Clauw, M.D.,
David A. Williams, Ph.D.,
Donald A. Robin, Ph.D.,
Eric M. Wassermann, M.D.

Pages:337–341
Published Online:16 August 2021

https://doi.org/10.1176/appi.neuropsych.20100255

Abstract
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Objective:Persistent fatigue is common among military servicemembers returning from deployment, especially those with a history of mild traumatic brain injury (mTBI). The purpose of this study was to characterize fatigue following deployment using the ...

Case Report

October 2021

Delayed-Onset Poststroke Psychosis Presenting as Delusional Disorder

Nichola R. Haddad, M.D.,
Rachel Caplan, M.D.,
Maria K. Houtchens, M.D.,
Stanley Lyndon, M.D.

Pages:342–344
Published Online:2 July 2021

https://doi.org/10.1176/appi.neuropsych.20100260

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October 2021

Functional Neurological Disorder After SARS-CoV-2 Vaccines: Two Case Reports and Discussion of Potential Public Health Implications

Matthew Butler, M.D.,
Jan Coebergh, M.D.,
Farinaz Safavi, Ph.D.,
Alan Carson, Ph.D.,
Mark Hallett, M.D.,
Benedict Michael, Ph.D.,
Thomas A. Pollak, Ph.D.,
Tom Solomon, Ph.D.,
Jon Stone, Ph.D.,
Timothy R. Nicholson, Ph.D.;
on behalf of the Coronerve Studies Group

Pages:345–348
Published Online:15 July 2021

https://doi.org/10.1176/appi.neuropsych.21050116

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Treatment in Behavioral Neurology & Neuropsychiatry

October 2021

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery

Christopher M. Filley, M.D.

Pages:349–355
Published Online:3 August 2021

https://doi.org/10.1176/appi.neuropsych.21030080

Abstract
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White matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic ...

October 2021

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium

Jo Ellen Wilson, M.D., M.P.H.,
Patricia Andrews, M.D.,
Aspen Ainsworth, M.D.,
Kamalika Roy, M.D.,
E. Wesley Ely, M.D., M.P.H.,
Mark A. Oldham, M.D.

Pages:356–364
Published Online:16 August 2021

https://doi.org/10.1176/appi.neuropsych.20120316

Abstract
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Objective:The phenotypes of several psychiatric conditions can very closely resemble delirium; the authors describe such presentations as pseudodelirium. However, because the clinical management of these conditions differs markedly from that of delirium, ...

Appreciation

October 2021

In Appreciation

Page:365
Published Online:28 October 2021

https://doi.org/10.1176/appi.neuropsych.330401

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