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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 34, Issue 3

July 2022

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Windows to the Brain

July 2022

Kisspeptin in the Limbic System: New Insights Into Its Neuromodulatory Roles

Wilfredo López-Ojeda, M.S., Ph.D., and
Robin A. Hurley, M.D.

Pages:190–195
Published Online:3 August 2022

https://doi.org/10.1176/appi.neuropsych.20220087

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Clinical Case Conference in Behavioral Neurology & Neuropsychiatry

July 2022

Case Study 2: A 60-Year-Old Man With Progressive Deficits in Language Output

Kristina Thurin, M.D.,
Viharkumar Patel, M.D.,
David L. Perez, M.D., M.M.Sc.,
Bradford C. Dickerson, M.D.,
Daisy Hochberg, M.S., C.C.C.-S.L.P.,
Megan Quimby, M.S., C.C.C.-S.L.P.,
Michael B. Miller, M.D., Ph.D.,
Mel Feany, M.D., Ph.D.,
David Silbersweig, M.D.,
Scott M. McGinnis, M.D.,
Kirk R. Daffner, M.D.,
Seth A. Gale, M.D.

Pages:196–203
Published Online:3 August 2022

https://doi.org/10.1176/appi.neuropsych.22010013

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Special Articles

July 2022

Central Executive Network and Executive Function in Patients With Alzheimer’s Disease and Healthy Individuals: Meta-Analysis of Structural and Functional MRI

Katrina M. Daigle, M.A., M.S.,
Malvina O. Pietrzykowski, M.S,
Abigail B. Waters, M.S.,
Lance P. Swenson, Ph.D.,
David A. Gansler, Ph.D.

Pages:204–213
Published Online:11 March 2022

https://doi.org/10.1176/appi.neuropsych.20110279

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Objective:The neural architecture of executive function is of interest given its utility as a transdiagnostic predictor of adaptive functioning. However, a gap exists in the meta-analytic literature assessing this relationship in neuropsychiatric ...

Articles

July 2022

Neuropsychiatric Symptoms in Dementia: Considering a Clinical Role for Electroencephalography

Simon Holmgren, M.D.,
Thomas Andersson, M.D., Ph.D.,
Anders Berglund, Ph.D.,
Dag Aarsland, M.D., Ph.D.,
Jeffrey Cummings, M.D., Sc.D.,
Yvonne Freund-Levi, M.D., Ph.D.

Pages:214–223
Published Online:21 March 2022

https://doi.org/10.1176/appi.neuropsych.21050135

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Objective:Degenerative dementia is characterized by progressive cognitive decline and neuropsychiatric symptoms. People with Alzheimer’s disease (AD), the most common cause of dementia, show synaptic loss and disruption of functional brain networks along ...

July 2022

A Double-Blind Placebo-Controlled, Randomized Trial of Divalproex Sodium for Posttraumatic Irritability Greater Than 1 Year After Mild to Moderate Traumatic Brain Injury

Thomas Beresford, M.D.,
Patrick J. Ronan, Ph.D.,
Daniel Hipp, Ph.D.,
Brandon Schmidt, M.A.,
E. Brie Thumm, Ph.D.,
Benjamin Temple,
Hal Wortzel, M.D.,
David Weitzenkamp, Ph.D.,
Chad Emrick, Ph.D.,
James Kelly, M.D., M.A.,
David B. Arciniegas, M.D.

Pages:224–232
Published Online:11 March 2022

https://doi.org/10.1176/appi.neuropsych.19070159

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Objective:Posttraumatic irritability after traumatic brain injury (TBI) may become a chronic problem and contribute to impaired everyday function, either alone or in combination with alcohol use disorder. The authors hypothesized that divalproex sodium (...

July 2022

Predicting New-Onset Psychiatric Disorders Throughout the COVID-19 Pandemic: A Machine Learning Approach

Daniela Caldirola, M.D., Ph.D.,
Francesco Cuniberti, M.D.,
Silvia Daccò, Psy.D.,
Massimiliano Grassi, Psy.D.,
Tatiana Torti, Psy.D.,
Giampaolo Perna, M.D., Ph.D.

Pages:233–246
Published Online:21 March 2022

https://doi.org/10.1176/appi.neuropsych.21060148

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Objective:The investigators estimated new-onset psychiatric disorders (PsyDs) throughout the COVID-19 pandemic in Italian adults without preexisting PsyDs and developed a machine learning (ML) model predictive of at least one new-onset PsyD in subsequent ...

July 2022

Treatment Patterns of Anxiety and Posttraumatic Stress Disorder Following Traumatic Brain Injury

Madeline R. Marks, Ph.D.,
Moira C. Dux, Ph.D.,
Vani Rao, M.D.,
Jennifer S. Albrecht, Ph.D.

Pages:247–253
Published Online:18 January 2022

https://doi.org/10.1176/appi.neuropsych.21040104

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Objective:Symptoms of mental disorders are common, are underrecognized, and contribute to worse outcomes after traumatic brain injury (TBI). Post-TBI, prevalence of anxiety disorders and prevalence of posttraumatic stress disorder (PTSD) are comparable ...

July 2022

Role of White Matter Microstructure in Impulsive Behavior

Eric L. Goldwaser, D.O., Ph.D.,
Xiaoming Du, Ph.D.,
Bhim M. Adhikari, Ph.D.,
Mark Kvarta, M.D., Ph.D.,
Joshua Chiappelli, M.D.,
Stephanie Hare, Ph.D.,
Wyatt Marshall, B.S.,
Anya Savransky, B.A.,
Kathleen Carino, B.S., B.A.,
Heather Bruce, M.D.,
Ashley Acheson, Ph.D.,
Peter Kochunov, Ph.D.,
L. Elliot Hong, M.D.

Pages:254–260
Published Online:18 January 2022

https://doi.org/10.1176/appi.neuropsych.21070167

Abstract
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Objective:Increased impulsivity is a hallmark trait of some neuropsychiatric illnesses, including addiction, traumatic brain injury, and externalizing disorders. The authors hypothesized that altered cerebral white matter microstructure may also ...

Clinical and Research Reports

July 2022

Exploring Cognitive Impairment in Patients With Bilateral Capsular Genu Lesions

Emre Kumral, M.D.,
Fatma Ece Çetin, M.D.,
Hüseyin Nezih Özdemir, M.D.,
Seyda Cankaya, M.D.,
Wolf-Rüdiger Schäbitz, M.D.,
Burak Yulug, M.D.

Pages:261–267
Published Online:18 January 2022

https://doi.org/10.1176/appi.neuropsych.21030086

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Objective:The authors investigated for presence of cognitive impairment after occurrence of bilateral lesions of the genu of the internal capsule (GIC). Clinical and neuropsychological features of unilateral GIC lesions have previously been studied, but ...

Case Reports

July 2022

Examination of the Proposed Criteria for Traumatic Encephalopathy Syndrome: Case Report of a Former Professional Football Player

Christian LoBue, Ph.D.,
C. Munro Cullum, Ph.D.,
John Hart, M.D.

Pages:268–274
Published Online:11 March 2022

https://doi.org/10.1176/appi.neuropsych.21090225

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Book Reviews

July 2022

Oxford Textbook of Neuropsychiatry

Lawren VandeVrede, M.D., Ph.D.

Page:275
Published Online:3 August 2022

https://doi.org/10.1176/appi.neuropsych.21010007

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Letters to the Editor

July 2022

Hysterectomy and Hormonal Dysregulation in Functional Neurological Disorder: A Comment on Stone et al., 2020

Timothy L. van Dijl, M.D.,
Diederik Smit, Ph.D., M.D.,
Arjan C. Videler, Ph.D.,
Willem J. Kop, Ph.D.

Pages:276–277
Published Online:3 August 2022

https://doi.org/10.1176/appi.neuropsych.21090236

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July 2022

Response to van Dijl et al.

Jon Stone, M.B. Ch.B., Ph.D.

Page:277
Published Online:3 August 2022

https://doi.org/10.1176/appi.neuropsych.21090236r

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Other Items of Interest

July 2022

2022 American Neuropsychiatric Association Annual Meeting Abstracts

Pages:278–302
Published Online:3 August 2022

https://doi.org/10.1176/appi.neuropsych.20223401

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