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Previous Issue Next Issue

The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 11, Issue 3

August 1999

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Windows to the Brain

August 1999

Normal Pressure Hydrocephalus: Significance of MRI in a Potentially Treatable Dementia

Robin A. Hurley, M.D.,
William G. Bradley, M.D., Ph.D.,
Haleema T. Latifi, M.D., and
Katherine H. Taber, Ph.D.

Pages:297–300
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.297

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Special Article

August 1999

Braincutting for Psychiatrists

Ronald Green, M.D.,
Ann Clark, Ph.D.,
William Hickey, M.D.,
Jeffrey Hutsler, Ph.D., and
Michael Gazzaniga, Ph.D.

Pages:301–306
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.301

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In the past two decades, neuroscientific investigations such as postmortem and neuroimaging studies have revealed a variety of regional brain disturbances in major mental illnesses. These emerging findings are difficult to appreciate fully without a ...

August 1999

The Neurobiology of Violence

Jan Volavka, M.D., Ph.D.

Pages:307–314
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.307

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Clinical correlates of violent behavior are known, but the underlying mechanisms are not well understood. This article reviews recent progress in the understanding of such mechanisms involving complex interactions between genes, prenatal and perinatal ...

August 1999

The Neuropsychiatry of Adult-Onset Adrenoleukodystrophy

Patricia I. Rosebush, M.Sc.N., M.D., F.R.C.P.C.,
Sarah Garside, M.D., Ph.D.,
Anthony J. Levinson, M.A., M.D., and
Michael F. Mazurek, M.D., F.R.C.P.C.

Pages:315–327
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.315

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Adrenoleukodystrophy is an inherited X-linked peroxisomal disorder that preferentially affects the adrenal cortex, testes, and brain and may occur at almost any age. Psychiatric symptomatology is present in many of the adult-onset cases reported in the ...

Regular Article

August 1999

Propranolol Treatment of Chronically Hospitalized Aggressive Patients

Jonathan M. Silver, M.D.,
Stuart C. Yudofsky, M.D.,
Jonathan A. Slater, M.D.,
Ruth Kugelmass Gold, M.D.,
Barri L. Katz Stryer, M.D.,
Daniel T. Williams, M.D.,
Henrietta Wolland, M.A., and
Jean Endicott, Ph.D.

Pages:328–335
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.328

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Violent behavior in psychiatric patients may result in long-term hospitalization. There is no FDA-approved psychopharmacologic treatment for aggression. In this study, 20 chronically aggressive hospitalized patients were administered 1 week of placebo ...

August 1999

Risperidone Treatment of Behavioral Disturbances in Outpatients With Dementia

Michael C. Irizarry, M.D.,
S. Nassir Ghaemi, M.D.,
Erica R. Lee-Cherry, B.A.,
Teresa Gomez-Isla, M.D., Ph.D.,
Giuliano Binetti, M.D.,
Bradley T. Hyman, M.D., Ph.D., and
John H. Growdon, M.D.

Pages:336–342
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.336

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The authors retrospectively assessed the effectiveness and side effects of risperidone used to treat behavioral disturbances in elderly outpatients with dementia. In 41 patients treated with risperidone 1.8±1.4 mg/day, there was complete suppression of ...

August 1999

Neurological Function During Long-Term Therapy With Recombinant Interferon Alpha

Norbert Mayr, M.D.,
Josef Zeitlhofer, M.D.,
Lüder Deecke, M.D.,
Elke Fritz,
Heinz Ludwig, M.D., and
Heinz Gisslinger, M.D.

Pages:343–348
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.343

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In 14 patients with myeloproliferative disorders associated with thrombocytosis, neurological and neuropsychological function were monitored prior to therapy with recombinant human interferon alpha (rIFN; dose 25 mU/week; range 10–35 mU/week) and after 3, ...

August 1999

CSF Thyrotropin-Releasing Hormone Gender Difference

Mark A. Frye, M.D.,
Keith A. Gary, Ph.D.,
Lauren B. Marangell, M.D.,
Mark S. George, M.D.,
Ann M. Callahan, M.D.,
John T. Little, M.D.,
Teresa Huggins, Ph.D.,
Gabriela Corá-Locatelli, M.D.,
Elizabeth A. Osuch, M.D.,
Andrew Winokur, M.D., Ph.D., and
Robert M. Post, M.D.

Pages:349–353
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.349

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In light of the postulated role of thyrotropin-releasing hormone (TRH) as an endogenous antidepressant, 56 refractory mood-disordered patients and 34 healthy adult control subjects underwent lumbar puncture for cerebrospinal fluid (CSF) TRH analysis. By ...

August 1999

Nocturnal Hormone Secretion and the Sleep EEG in Patients Several Months After Traumatic Brain Injury

Ralf-Michael Frieboes, M.D.,
Ulrich Müller, M.D.,
Harald Murck, M.D.,
D. Yves von Cramon, M.D.,
Florian Holsboer, M.D., Ph.D., and
Axel Steiger, M.D.

Pages:354–360
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.354

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After severe traumatic brain injury (TBI), sleep disturbances and changes in hormone secretion are frequently observed. Similarly, in depression, abnormalities of sleep and neuroendocrine regulation are common. To test the hypothesis that the changes in ...

August 1999

Dose-Related Neurobehavioral Effects of Chronic Cocaine Use

Karen I. Bolla, Ph.D.,
Richard Rothman, M.D. Ph.D., and
Jean Lud Cadet, M.D.

Pages:361–369
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.361

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Although cocaine use is a significant public health problem, there is a paucity of scientific data on long-term neurobehavioral effects. This study examined the dose-related association between chronic cocaine use and neurobehavioral performance. A ...

August 1999

Lateralization of Facial Emotional Expression in Schizophrenic and Depressed Patients

Sandra Yecker, Ph.D.,
Joan C. Borod, Ph.D.,
Alizah Brozgold, Ph.D.,
Candace Martin, Ph.D.,
Murray Alpert, Ph.D., and
Joan Welkowitz, Ph.D.

Pages:370–379
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.370

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This study examined facial emotional expressions produced by schizophrenic (SZ), unipolar depressed (UD), and normal control (NC) right-handed adults. Hypotheses regarding right-hemisphere activation in UD and suppression in SZ were addressed, as well as ...

August 1999

Interictal ¹⁸FDG PET Findings in Temporal Lobe Epilepsy With Déjà vu

Naoto Adachi, M.D.,
Michael Koutroumanidis, M.D.,
Robert D.C. Elwes, M.D.,
Charles E. Polkey, M.D.,
Colin D. Binnie, M.D., Ph.D.,
Edward H. Reynolds, M.D.,
Sally F. Barrington, M.D.,
Michael N. Maisey, M.D., and
Chrysostomos P. Panayiotopoulos, M.D.

Pages:380–386
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.380

Abstract
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The authors studied the functional anatomy of the déjà vu (DV) experience in nonlesional temporal lobe epilepsy (TLE), using interictal fluorine-18 fluorodeoxyglucose PET in 14 patients with and 17 patients without DV. Several clinical conditions, such as ...

August 1999

Spatial Working Memory in Asymptomatic HIV-Infected Subjects

Barbara Grassi, M.D.,
Giacomo Garghentini, Ph.D.,
Arturo Campana, M.D.,
Elena Grassi, Ph.D.,
Sara Bertelli, M.D.,
Paola Cinque, M.D.,
Mara Epifani, M.D.,
Adriano Lazzarin, M.D., and
Silvio Scarone, M.D.

Pages:387–391
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.387

Abstract
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Many clinical and research findings converge to indicate that frontal lobe, basal ganglia, and related neuronal connections are primarily involved in human immunodeficiency virus (HIV) infection; frontal lobe, mainly the prefrontal cortex, has a ...

Clinical and Research Reports

August 1999

Olanzapine for Psychosis in Patients With Parkinson's Disease With and Without Dementia

D. Aarsland, M.D., Ph.D.,
J. P. Larsen, M.D., Ph.D.,
N. G. Lim, M.D., and
E. Tandberg, M.D.

Pages:392–394
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.392

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Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine. Eight subjects had dementia. Six subjects (29%) discontinued treatment prematurely because of drowsiness. Delusions and hallucinations ...

August 1999

Reduced Design Fluency in Subclinical Obsessive-Compulsive Subjects

David Mataix-Cols, B.Psychol.,
Maite Barrios, B.Psychol.,
Miquel Sànchez-Turet, M.D.,
Julio Vallejo, M.D., and
Carme Junqué, Ph.D.

Pages:395–397
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.395

Abstract
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This study examined the verbal and design fluency abilities of 25 subclinical obsessive-compulsive (OC) subjects and 27 noncompulsive control subjects. As hypothesized, the OC group showed reduced design fluency, and design fluency was also negatively ...

August 1999

Are Musical Obsessions a Temporal Lobe Phenomenon?

Nompumelelo Zungu-Dirwayi, B.A.,
Frans Hugo, M.B.,
Ben B. van Heerden, M.B., and
Dan J. Stein, M.B.

Pages:398–400
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.398

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Obsessive musical tunes have been described in some cases of obsessive-compulsive disorder (OCD). The authors present 2 cases of patients with musical obsessions, including findings from functional brain imaging. Both patients, 1 with idiopathic OCD and 1 ...

Neuropsychiatric Practice and Opinion

August 1999

Limitations of the American Academy of Neurology and American Clinical Neurophysiology Society Paper on QEEG

Daniel A. Hoffman, M.D.,
Joel F. Lubar, Ph.D.,
Robert W. Thatcher, Ph.D.,
M. Barry Sterman, Ph.D.,
Peter J. Rosenfeld, Ph.D.,
Sebastian Striefel, Ph.D.,
David Trudeau, M.D., and
Steve Stockdale, Ph.D.

Pages:401–407
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.401

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Calendar

August 1999

Page:408
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.408

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Book Reviews

August 1999

Practitioner's Guide to the Neuropsychiatry of HIV/AIDS

Jon A. Levenson, M.D.

Pages:409–410
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.409

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Letter

August 1999

Bilingualism and Dementia

Mario F. Mendez, M.D., Ph.D.,
Kent M. Perryman, Ph.D.,
Marcel O. PontÓn, Ph.D., and
Jeffrey L. Cummings, M.D., Los Angeles, CA

Pages:411–412
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.411

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August 1999

Schizophrenia-Like Symptoms in the Westphal-Strümpell Form of Wilson's Disease

Jürgen L. MüLLER, M.D., Regensburg, Germany

Page:412
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.412

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August 1999

“Miraculous” Recovery from Severe Chronic Psychosis After Coma From Septicemia

David Behar, M.D., Philadelphia, PA,
James Schaller, M.D.,
Deborah Easter, B.A., and
Mary Hofmann, Downingtown, PA

Pages:412-a–413
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.412-a

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August 1999

Depression-Dependent Tardive Dyskinesia

AndrÉs HerrÁn, M.D., and
Jose Luis VÁzquez-Barquero, Ph.D., Santander, Spain

Pages:413–414
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.413

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August 1999

Lithium-Treated Mood Disorders, Paroxysmal Rhinorrhea, and Mesial Temporal Lobe Epilepsy

Jon Berner, M.D., Ph.D., Woodinville, WA

Pages:414–415
Published Online:1 August 1999

https://doi.org/10.1176/jnp.11.3.414

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