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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 10, Issue 4

November 1998

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Special Article

November 1998

Delusions in Alzheimer's Disease

Vani Rao, M.D., and
Constantine G. Lyketsos, M.D., M.H.S.

Pages:373–382
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.373

Abstract
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Alzheimer's disease is the leading cause of mental impairment in elderly people, accounting for a large proportion of admissions to nursing homes and assisted living homes. Psychiatric symptoms associated with Alzheimer's disease, although common, have ...

November 1998

Considering the Role of the Amygdala in Psychotic Illness

Julie L. Fudge, M.D.,
James M. Powers, M.D.,
Suzanne N. Haber, Ph.D., and
Eric D. Caine, M.D.

Pages:383–394
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.383

Abstract
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For many years, the structures of the medial temporal lobe have been implicated in the pathogenesis of schizophrenia. Recent hypotheses, based on data from MRI and functional imaging, propose that disruption of frontotemporal neural networks may be an ...

November 1998

The Neurologic Examination in Adult Psychiatry

Richard D. Sanders, M.D., and
Matcheri S. Keshavan, M.D.

Pages:395–404
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.395

Abstract
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Of the proliferating approaches to neuropsychiatric assessment, a relatively neglected technique is the venerable, accessible, noninvasive, and inexpensive neurologic examination. This article organizes and synthesizes the literature on neurological ...

Regular Article

November 1998

Lewy Body Disease

Michelle Papka, Ph.D.,
Ana Rubio, M.D., Ph.D.,
Randolph B. Schiffer, M.D., and
Christopher Cox, Ph.D.

Pages:405–412
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.405

Abstract
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The authors assessed the accuracy of published clinical criteria and their own modifications of those criteria in diagnosing Lewy body disease (LBD). Clinical diagnoses were made by two clinicians, blinded to neuropathologic diagnoses, using the Rochester ...

November 1998

Clinical and Physiological Effects of Stereotaxic Bilateral Amygdalotomy for Intractable Aggression

Gregory P. Lee, Ph.D.,
Antoine Bechara, Ph.D.,
Ralph Adolphs, Ph.D.,
John Arena, Ph.D.,
Kimford J. Meador, M.D.,
David W. Loring, Ph.D., and
Joseph R. Smith, M.D.

Pages:413–420
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.413

Abstract
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The amygdala is thought to be an important neural structure underlying the “fight-or-flight” response, but information on its role in humans is scarce. The clinical and psychophysiological effects of amygdalar destruction were studied in 2 patients who ...

November 1998

Prevalence and Correlates of Aggressive Behavior in Alzheimer's Disease

Erán Chemerinski, M.D.,
Gustavo Petracca, M.D.,
Alejandra Tesón, Ph.D.,
Liliana Sabe, Ph.D.,
Ramón Leiguarda, M.D., and
Sergio E. Starkstein, M.D., Ph.D.

Pages:421–425
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.421

Abstract
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The authors assessed a consecutive series of 196 patients with probable Alzheimer's disease (AD) for the presence of aggressive behavior, using a standardized neurological, neuropsychiatric, and neuropsychological battery that included both the Overt ...

November 1998

Executive Dysfunction in Alzheimer's Disease

Stephen T. Chen, M.D.,
David L. Sultzer, M.D.,
Charles H. Hinkin, Ph.D.,
Michael E. Mahler, M.D., and
Jeffrey L. Cummings, M.D.

Pages:426–432
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.426

Abstract
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Relationships between measures of executive skills and neuropsychiatric and functional status were examined in a group of 31 patients with Alzheimer's disease. Deficits in four executive skills tests were significantly associated with the Agitation/...

November 1998

Alteration of Regional Cerebral Glucose Utilization With Delusions in Alzheimer's Disease

Nobutsugu Hirono, M.D.,
Etsuro Mori, M.D.,
Kazunari Ishii, M.D.,
Hajime Kitagaki, M.D.,
Masahiro Sasaki, Ph.D.,
Yoshitaka Ikejiri, M.D.,
Toru Imamura, M.D.,
Tatsuo Shimomura, M.D.,
Manabu Ikeda, M.D., and
Hikari Yamashita, M.A.

Pages:433–439
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.433

Abstract
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The authors examined 65 patients with Alzheimer's disease for delusions and explored the relationship of delusions with regional cerebral glucose metabolism determined by [¹⁸F]fluorodeoxyglucose PET. In patients with delusions (n=26), normalized glucose ...

November 1998

Relationship of Cognitive and Functional Impairment to Depressive Features in Alzheimer's Disease and Other Dementias

Jennifer L. Payne, M.D.,
Constantine G. Lyketsos, M.D., M.H.S.,
Cynthia Steele, R.N., M.P.H.,
Lori Baker, B.A.,
Elizabeth Galik, R.N., M.S.N.,
Susan Kopunek, R.N.,
Martin Steinberg, M.D., and
Andrew Warren, M.B.B.S.

Pages:440–447
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.440

Abstract
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Patients with clinical diagnoses of Alzheimer's disease, vascular dementia, or undifferentiated dementia were rated on standardized measures of depression, cognitive impairment, and functional impairment. Logistic regression was used to evaluate the ...

November 1998

A Longitudinal Study of Psychosis due to a General Medical (Neurological) Condition

Anthony Feinstein, M.Phil., Ph.D., F.R.C.P.C., and
Maria Ron, M.Phil., Ph.D., F.R.C.Psych.

Pages:448–452
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.448

Abstract
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A sample of 44 patients with a neurological disorder and a DSM-IV diagnosis of Psychosis due to a General Medical Condition were followed on average for 4 years and their response to treatment and clinical course noted. Outcome was more benign than in ...

Clinical and Research Report

November 1998

Rapid Response of Emotional Incontinence to Selective Serotonin Reuptake Inhibitors

Ziad Nahas, M.D.,
Kimberly A. Arlinghaus, M.D.,
Kathryn J. Kotrla, M.D.,
Rebecca R. Clearman, M.D., and
Mark S. George, M.D.

Pages:453–455
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.453

Abstract
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Emotional incontinence (EI) is a perturbing condition characterized by uncontrollable outbursts of exaggerated, involuntary facial expressions and pathological crying or laughter. There is increasing evidence that serotonergic neurotransmission may be ...

November 1998

Psychotic Symptoms in Dementia Associated With Motor Neuron Disease

Ricardo Nitrini, M.D., and
Sérgio Rosemberg, M.D.

Pages:456–458
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.456

Abstract
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Three patients with neuropathologically confirmed frontotemporal dementia, motor neuron disease type, manifested hallucinations. In this dementia, the superficial layers of the frontal and temporal cortices are predominantly affected. Hallucinations may ...

Neuropsychiatric Practice and Opinion

November 1998

Handedness and Cerebral Dominance

Marian Annett, D.Sc.

Pages:459–469
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.459

First Page
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Book Review

November 1998

Contemporary Behavioral Neurology (Blue Books of Practical Neurology, Vol. 16)

Jane Epstein, M.D.

Pages:470–471
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.470

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Letter

November 1998

Delusional Jealousy and Localized Cerebral Pathology

Michael Soyka, M.D., Psychiatric Hospital, University of Munich, Munich, Germany

Page:472
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.472

First Page
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November 1998

Facial Myocloni and Stroke as Late Sequelae of Metrizamide Myelography

J. Finsterer,
D. Lubec, Ludwig Boltzmann Institute for Research in Epilepsy and Neuromuscular Disorders, Vienna, Austria,
A. Verlicchi, Scuola di Specialita di Neurologia, University of Bologna, Italy, and
P. Samec, Department of Radiology, NKH Rosenhügel, Vienna, Austria

Pages:472a–473
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.472a

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November 1998

Should Risperidone Be Used in Parkinson's Disease?

Joseph H. Friedman, M.D., and
Brian R. Ott, M.D., Department of Clinical Neurosciences, Brown University School of Medicine, Providence, RI

Pages:473–474
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.473

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November 1998

Richard H. Workman, M.D., Houston VA Medical Center and Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX

Pages:474–475
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.474

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November 1998

Religious Experience Was Not Correctly Defined

Michael Kozart, M.D., UCLA Neuropsychiatric Institute, Center for the Health Sciences, Los Angeles, CA

Page:475
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.475

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November 1998

Jeffrey L. Saver, M.D., UCLA-Reed Neurologic Research Center, Los Angeles, CA, and
John Rabin, M.D., UCLA Neuropsychiatric Institute, Los Angeles, CA

Pages:475a–476
Published Online:1 November 1998

https://doi.org/10.1176/jnp.10.4.475a

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