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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 17, Issue 1

February 2005

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Windows to the Brain

February 2005

Neural Underpinnings of Fear and Its Modulation: Implications for Anxiety Disorders

Lisa A. Miller, M.D.,
Katherine H. Taber, Ph.D.,
Glen O. Gabbard, M.D., and
Robin A. Hurley, M.D.

Pages:1–6
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.1

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Special Article

February 2005

Apathy: Why Care?

Robert van Reekum, M.D., F.R.C.P.C.,
Donald T. Stuss, Ph.D., and
Laurie Ostrander, R.N.

Pages:7–19
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.7

Abstract
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This review presents data showing that apathy is common across a number of disorders. Apathy is not only common, but is also associated with significant problems: reduced functional level, decreased response to treatment, poor illness outcome, caregiver ...

February 2005

Mood Disorders and Their Treatment in Patients With Epilepsy

Christian Prueter, M.D., and
Christine Norra, M.D.

Pages:20–28
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.20

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Mood disorders in patients with epilepsy are not frequently diagnosed and not treated. Because of the high prevalence of depression and the resulting high suicide rate, precise diagnosis and effective therapy are very important. Frequently, the clinical ...

Regular Article

February 2005

The Overt Aggression Scale for Rating Aggression in Outpatient Youth With Autistic Disorder: Preliminary Findings

Jessica A. Hellings, M.D.,
Elizabeth J. Nickel, M.A.,
Marilyn Weckbaugh, R.N.,
Kevin McCarter, Ph.D.,
Michael Mosier, Ph.D., and
Stephen R. Schroeder, Ph.D.

Pages:29–35
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.29

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Aggression is a common and costly problem in youth with developmental disabilities. Rating scales that accurately capture and measure subtypes of aggression phenomenology, frequency and severity are urgently needed, in both clinical practice and research. ...

February 2005

Clozapine Reduces Violent Behavior in Heterogeneous Diagnostic Groups

John E. Kraus, M.D., Ph.D., and
Brian B. Sheitman, M.D.

Pages:36–44
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.36

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Violent behavior is a significant problem in the psychiatric hospital setting. Persistently violent patients often require seclusion and/or restraints and typically receive high doses of medication and polypharmacy. Clozapine has been found to be ...

February 2005

Characterizing the Emotions That Trigger Cataplexy

Lois E. Krahn, M.D.,
James F. Lymp, Ph.D.,
Wendy R. Moore, R.N.,
Nancy Slocumb, and
Michael H. Silber, M.D.

Pages:45–50
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.45

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Cataplexy is an intriguing example of how emotions can trigger muscle weakness by activating neural pathways. When associated with excessive daytime sleepiness, cataplexy is considered pathognomonic of narcolepsy. A questionnaire was administered to 55 ...

February 2005

Independence of Changes in Behavior From Cognition and Function in Community-Dwelling Persons With Alzheimer’s Disease: A Factor Analytic Approach

Rochelle E. Tractenberg, Ph.D., M.P.H.,
Myron F. Weiner, M.D.,
Jeffrey L. Cummings, M.D.,
Marian B. Patterson, Ph.D., and
Leon J. Thal, M.D.

Pages:51–60
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.51

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The authors’ main objective was to investigate the relationship between changes in psychopathological, cognitive and activity of daily living (ADL) instrument scores over 12 months in community-dwelling persons with Alzheimer’s disease (AD). A secondary ...

February 2005

Cognitive Impairment Associated With Major Depression Following Mild and Moderate Traumatic Brain Injury

Mark J. Rapoport, M.D., F.R.C.P.C.,
Scott McCullagh, M.D., F.R.C.P.C.,
Prathiba Shammi, Ph.D., and
Anthony Feinstein, Ph.D., F.R.C.P.C.

Pages:61–65
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.61

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Traumatic brain injury (TBI) and major depression are neuropsychiatric conditions that have been associated with cognitive dysfunction. The aim of this study was to explore the relationship between major depression and cognitive impairment following mild ...

February 2005

Deficits in Social Knowledge Following Damage to Ventromedial Prefrontal Cortex

Linda W.Y. Mah, M.D.,
Miriam Courtney Arnold, Ph.D., and
Jordan Grafman, Ph.D.

Pages:66–74
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.66

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Patients with damage to the frontal lobes frequently exhibit impaired social behavior, but it is not clear which specific processes are disrupted. The authors investigated the ability to interpret nonverbal emotional expression in patients with lesions ...

February 2005

Increasing Memory Load Modulates Regional Brain Activity in Older Adults as Measured by fMRI

Jeffrey R. Petrella, M.D.,
Brent A. Townsend, B.S.,
Amishi P. Jha, Ph.D.,
Lauretta A. Ziajko, M.D.,
Melissa J. Slavin, Ph.D.,
Cindy Lustig, Ph.D.,
Sarah J. Hart, B.S., and
P. Murali Doraiswamy, M.D.

Pages:75–83
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.75

Abstract
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Several recent studies using functional magnetic resonance imaging (fMRI) during recognition memory tests have suggested that the ability to neuromodulate as a function of cognitive demand may be impaired in older adults due to age-related cell loss and ...

February 2005

Normative Data for the Unquantified EEG: Examination of Adequacy for Neuropsychiatric Research

Nashaat Boutros, M.D.,
Hugh A. Mirolo, M.D., and
Frederick Struve, Ph.D.

Pages:84–90
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.84

Abstract
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Visual inspection of the unquantified electroencephalogram (EEG) remains the sole technique to confidently detect epileptiform discharges. Usefulness of this procedure in psychiatric research is hampered by reported prevalence of abnormalities in normal ...

February 2005

The Neuropsychiatry and Multisystem Features of the Smith-Magenis Syndrome: A Review

Bhaskara P. Shelley, M.B.B.S., M.D., D.M., and
Mary M. Robertson, M.B.Ch.B., M.D., D.P.M., M.R.C.P., M.R.C.P.H., F.R.C.Psych.

Pages:91–97
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.91

Abstract
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Smith-Magenis Syndrome (SMS) is a complex, pediatric, neurobehavioral, contiguous gene syndrome ascribed to interstitial microdeletion of chromosome 17, band 11.2. The syndrome is characterized by distinctive behavioral, neurocognitive, and ...

February 2005

Self-Administered Screening for Mild Cognitive Impairment: Initial Validation of a Computerized Test Battery

Jane B. Tornatore, Ph.D.,
Emory Hill, Ph.D.,
Jo Anne Laboff, M.S.W., and
Mary E. McGann, M.P.H., M.S.W.

Pages:98–105
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.98

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The Computer-Administered Neuropsychological Screen for Mild Cognitive Impairment (CANS-MCI), a computer administered, scored, and interpreted touch screen battery was evaluated for its ability to detect mild cognitive impairment. Subjects were three ...

February 2005

Intellectual Functioning in Adolescents With Indicators of Psychosis: Evidence for Decline in Functioning Related to Number of Psychotic Features?

Lale Bilginer, Ph.D.,
Victoria DeLuca, Ph.D.,
David L. Pogge, Ph.D.,
John S. Stokes, Ph.D., and
Philip D. Harvey, Ph.D.

Pages:106–113
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.106

Abstract
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Substantial research has demonstrated that adults with schizophrenia display intellectual decline compared to their premorbid levels of functioning. Research of this type, however, is not as common in adolescents with psychotic disorders. Since many first-...

Clinical and Research Reports

February 2005

Apathy Correlates With Cognitive Function But Not CD4 Status in Patients With Human Immunodeficiency Virus

Robert Paul, Ph.D.,
Timothy P. Flanigan, M.D.,
Karen Tashima, M.D.,
Ronald Cohen, Ph.D.,
Jay Lawrence, B.A.,
Elizabeth Alt, B.A.,
David Tate, Ph.D.,
Corrine Ritchie, and
Charles Hinkin, Ph.D.

Pages:114–118
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.114

Abstract
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Apathy is a prominent neuropsychiatric symptom associated with human immunodeficiency virus (HIV). The increased frequency of apathy in this population may reflect the direct involvement of the virus on the central nervous system (CNS), but the severity ...

February 2005

Huntington’s Disease Patients Show Impaired Perception of Disgust in the Gustatory and Olfactory Modalities

I. J. Mitchell, D.Phil.,
H. Heims, B.Sc.,
E. A. Neville, B.Sc., and
H. Rickards, M.D.

Pages:119–121
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.119

Abstract
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Patients with Huntington’s disease show deficits in recognizing disgust in the facial expressions and vocal intonations of others. In this study, the authors demonstrate that these disgust-related deficits extend to foul-smelling olfactory stimuli and ...

Letter

February 2005

Secondary Mania Following Traumatic Brain Injury

Bilici Mustafa, M.D.,
Özkorumak Evrim, M.D., and
Ahmet Sarı, M.D., Karadeniz Technical Univercity, School of Medicine, Department of Psychiatry, and Radiology, Trabzon, Türkiye.

Pages:122–124
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.122

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February 2005

Of Illusions, Hallucinations and Creutzfeldt-Jakob Disease (Heidenhain's Variant)

Harpal K. Brar, M.D.,
Vaishnavi Vaddigiri, M.D., and
Angela Scicutella, M.D., Ph.D., Long Island Jewish Medical Center, Department of Geriatric Psychiatry, 75-59 263rd Street, Glen Oaks, NY 11004

Pages:124–126
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.124

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February 2005

Peripheral Circulatory Disturbance Induced by Milnacipran

Mitsuhiro Kamata, M.D., Department of Psychiatry, Yuri Kumiai General Hospital, 38, Aza-Yago, Kawaguchi, Honjo City, Akita, 015-8511, Japan, and
Hisashi Higuchi, M.D., Department of Psychiatry, Omagari City Hospital, 210, Aza-Sekihigashi, Iida, Omagari City, Akita, 014-0067, Japan

Pages:126–127
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.126

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Calendar

February 2005

Page:128
Published Online:1 February 2005

https://doi.org/10.1176/jnp.17.1.128

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