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The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 14, Issue 3

August 2002

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Windows to the Brain

August 2002

Predicting Treatment Response in Obsessive-Compulsive Disorder

Robin A. Hurley, M.D.,
Sanjaya Saxena, M.D.,
Scott L. Rauch, M.D.,
Rudolf Hoehn-Saric, M.D., and
Katherine H. Taber, Ph.D.

Pages:249–253
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.249

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Special Article

August 2002

Memory Mechanisms in Posttraumatic Stress Disorder

Barry Layton, Ph.D., and
Robert Krikorian, Ph.D.

Pages:254–261
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.254

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The authors present a new theory of the neurobiological mechanisms mediating the memory processes involved in posttraumatic stress disorder (PTSD). The current fear-conditioning model accounts for learning that underlies certain central features of PTSD, ...

Regular Article

August 2002

Subcortical Hyperintensities in Alzheimer's Disease

David L. Sultzer, M.D.,
Stephen T. Chen, M.D.,
Charles V. Brown, M.D.,
Michael E. Mahler, M.D.,
Jeffrey L. Cummings, M.D.,
Charles H. Hinkin, Ph.D., and
Mark A. Mandelkern, M.D., Ph.D.

Pages:262–269
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.262

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The authors measured subcortical hyperintensities (SH) on magnetic resonance images (MRI) in 18 patients with probable Alzheimer's disease and examined the relationships of SH severity with cortical metabolic function and clinical symptoms. Severity of SH ...

August 2002

Repetitive Transcranial Magnetic Stimulation Treatment of Comorbid Posttraumatic Stress Disorder and Major Depression

Paul B. Rosenberg, M.D.,
Ritula B. Mehndiratta, M.D.,
Yash P. Mehndiratta, M.D.,
Angela Wamer, M.D.,
Richard B. Rosse, M.D., and
Marshall Balish, M.D., Ph.D.

Pages:270–276
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.270

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Twelve patients with comorbid posttraumatic stress disorder (PTSD) and major depression underwent repetitive transcranial magnetic stimulation (rTMS) to left frontal cortex as an open-label adjunct to current antidepressant medications. rTMS parameters ...

August 2002

Cerebral Blood Flow Changes Associated With Schneiderian First-Rank Symptoms in Schizophrenia

Nicolas Franck, M.D.,
Daniel S. O'Leary, Ph.D.,
Michael Flaum, M.D.,
Richard D. Hichwa, Ph.D., and
Nancy C. Andreasen, M.D., Ph.D.

Pages:277–282
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.277

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The authors examined the severity of Schneiderian first-rank symptoms in relation to regional cerebral blood flow (rCBF) with the use of PET. Eighty-seven schizophrenic patients were imaged during an eyes-closed condition during which they were instructed ...

August 2002

Limbic System Function and Dream Content in University Students

Nichol D.J. Peterson, B.A. (Hon.Psych.),
Peter G. Henke, Ph.D., and
Zoe Hayes, Ph.D.

Pages:283–288
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.283

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This study explored the relationship between limbic system function and threatening dream content. Recently it has been proposed that dreams are an evolutionary mechanism designed to facilitate the rehearsal of coping strategies in dangerous situations. ...

August 2002

A Randomized, Double-Blind, Crossover Study of Methylphenidate and Lithium in Adults With Attention-Deficit/Hyperactivity Disorder

María Flavia Dorrego, Ph.D.,
Lilia Canevaro, M.D.,
Gabriela Kuzis, Ph.D.,
Liliana Sabe, Ph.D., and
Sergio E. Starkstein, M.D., Ph.D.

Pages:289–295
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.289

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The authors examined the efficacy of methylphenidate (MPH) and lithium to treat attention-deficit/ hyperactivity disorder (ADHD) in adults, using a randomized, double-blind, crossover design. Patients received 8 weeks of MPH treatment (up to 40 mg/day) ...

August 2002

Behavioral Problems as Predictors of Functional Abilities of Vascular Dementia Patients

Tricia M. Zawacki, Ph.D.,
Janet Grace, Ph.D.,
Robert Paul, Ph.D.,
David J. Moser, Ph.D.,
Brian R. Ott, M.D.,
Norman Gordon, M.D., and
Ronald A. Cohen, Ph.D.

Pages:296–302
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.296

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The relationship of behavioral disturbance and dementia severity to activities of daily living (ADLs) in vascular dementia (VaD) was examined in baseline data for 29 VaD patients. A series of stepwise regression analyses was conducted to examine the ...

August 2002

Investigating Emergent Symptomatology as an Outcome Measure in a Behavioral Study of Alzheimer's Disease

Rochelle E. Tractenberg, Ph.D., M.P.H.,
Anthony Gamst, Ph.D.,
Ronald G. Thomas, Ph.D.,
Marian Patterson, Ph.D.,
Lon S. Schneider, M.D., and
Leon J. Thal, M.D.

Pages:303–310
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.303

Abstract
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These retrospective analyses represent a pilot study of a potential new outcome, expected emergence. The Behavior Rating Scale for Dementia (BRSD) was administered at the baseline and 12-month visits of a multicenter study. The authors computed the rates ...

August 2002

Errors Produced on the Mini-Mental State Examination and Neuropsychological Test Performance in Alzheimer's Disease, Ischemic Vascular Dementia, and Parkinson's Disease

Angela L. Jefferson, M.S.,
Stephanie A. Cosentino, M.S.,
Susan K. Ball, M.D.,
Bruce Bogdanoff, M.D.,
Norman Leopold, D.O.,
Edith Kaplan, Ph.D., and
David J. Libon, Ph.D.

Pages:311–320
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.311

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The authors investigated whether MMSE indices designed to measure temporal and physical orientation, declarative memory, language, working memory, and motor/constructional function could differentiate patients with different dementia diagnoses: Alzheimer'...

August 2002

Neurological Basis of Deficits in Affective Prosody Comprehension Among Alcoholics and Fetal Alcohol–Exposed Adults

Marilee Monnot, Ph.D.,
William R. Lovallo, Ph.D.,
Sara Jo Nixon, Ph.D., and
Elliott Ross, M.D.

Pages:321–328
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.321

Abstract
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Affective prosody is a nonlinguistic aspect of language that conveys emotions and attitudes during discourse. In this study the neurological basis of affective prosodic comprehension (APC) dysfunction in alcoholics (ALC) and fetal alcohol–exposed adults (...

August 2002

Disease-Specific Properties of the Hamilton Rating Scale for Depression in Patients With Stroke, Alzheimer's Dementia, and Parkinson's Disease

Paul Naarding, M.D.,
Albert F. G. Leentjens, M.D.,
Fop van Kooten, M.D., and
Frans R.J. Verhey, M.D., Ph.D.

Pages:329–334
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.329

Abstract
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To compare the psychometric properties of the Hamilton Rating Scale for Depression (Ham-D) in patients with stroke, Alzheimer's dementia (AD), and Parkinson's disease (PD), receiver operating characteristic curves were plotted for each group. The ...

August 2002

Psychiatric Features and Disturbance of Circadian Rhythm of Temperature, Pulse, and Blood Pressure in Wilson's Disease

Eneida B. Matarazzo, M.D., Ph.D.

Pages:335–339
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.335

Abstract
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Wilson's disease (hepatolenticular degeneration), a disease of genetic origin, is due to abnormal copper metabolism affecting many organs and systems, especially the liver and the nervous system. The initial symptoms can be exclusively or predominantly ...

Clinical and Research Reports

August 2002

SPECT Scans in Identical Twins With Trichotillomania

Bavanisha Vythilingum, M.B.,
James Warwick, M.B.,
Jeanine van Kradenburg, R.N.,
Charmaine Hugo, B.A.,
Ben van Heerden, M.B., and
Dan J. Stein, M.B.

Pages:340–342
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.340

Abstract
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SPECT scans of a set of twins with trichotillomania showed that the twin with more severe disease had larger perfusion defects, involving more areas on the scan. Prospective brain imaging studies of twins may provide useful information about the ...

Neuropsychiatric Practice and Opinion

August 2002

Geriatric Treatment Center

Christopher M. Filley, M.D.,
David B. Arciniegas, M.D.,
G. Vernon Wood, Ph.D.,
C. Alan Anderson, M.D.,
Elisabeth Cheney, M.D.,
Charles R. Dygert, M.D.,
Lanier Summerall, M.D., and
Robert B. Goos, M.D.

Pages:344–350
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.344

Abstract
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The diagnosis and treatment of individuals with problems involving both psychiatry and neurology have become more sophisticated in recent years, but these advances may be difficult to implement in the modern health care environment. For 16 years, an ...

Book Reviews

August 2002

Neuroanatomy Through Clinical Cases

José G. Merino, M.D., M.Phil., and
Andrés Martin, M.D., M.P.H.

Pages:351–352
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.351

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August 2002

Cognitive Rehabilitation: An Integrative Neuropsychological Approach

Michelle Kornbleuth, Ph.D.

Page:352
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.352

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Letter

August 2002

Educating Patients About Symptoms of Anxiety in the Wake of Neurological Illness

Frank M. Dattilio, Ph.D., Harvard Medical School, Boston, MA

Pages:354–355
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.354

First Page
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August 2002

Marked Improvement of Meige's Syndrome With Olanzapine in a Schizophrenic Patient

Hiroki Fukui, M.D., Department of Psychiatry, Obama Public Hospital, Obama, Japan, and
Toshiya Murai, M.D., Department of Psychiatry, Faculty of Medicine, Kyoto University, Kyoto, Japan

Pages:355–356
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.355

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August 2002

Prominent Echolalia From Isolation of the Speech Area

Mario F. Mendez, M.D., Ph.D., Departments of Neurology and Psychiatry & Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA

Pages:356–357
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.356

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August 2002

Rapid Worsening of Depressive Symptoms in a Patient With Depression After Switching From a TCA to an SSRI

Kazuhiro Sato, M.D.,
Keizo Yoshida, M.D.,
Hisashi Higuchi, M.D., and
Tetsuo Shimizu, M.D., Department of Psychiatry, Akita University School of Medicine, Akita, Japan

Page:357
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.357

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August 2002

Fahr's Disease and Schizophrenia in a Patient With Secondary Hypoparathyroidism

Boro Ilievski, M.D.,
Krste Rodzevski, M.D.,
Miriam Gibbon, M.S., and
Andrew J. Dwork, M.D., Departments of Psychiatry (all) and Pathology (a.j.d.), Columbia University, New York, NY; Departments of Neuroscience (a.j.d., b.i., k.r.) and Biometrics (m.g.), New York State Psychiatric Institute, New York, NY

Pages:357-a–358
Published Online:1 August 2002

https://doi.org/10.1176/jnp.14.3.357-a

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